Portal de Periódicos da CAPES

Respiratory Alkalosis

1965; American Medical Association; Volume: 116; Issue: 5 Linguagem: Inglês

10.1001/archinte.1965.03870050053009

1538-3679

ALFRED EICHENHOLZ,

Gastroesophageal reflux and treatments

Introduction A PRIMARY reduction in the physically dissolved fraction of carbon dioxide in blood defines the state of primary respiratory alkalosis (primary hypocapnia). The quantity of physically dissolved CO 2 ([H 2 CO 3 ]) in blood depends on the partial pressure of CO 2 (P co 2 ). 1 Arterial blood P co 2 , is in equilibrium with pulmonary alveolar air P co 2 , which in turn is directly proportional to alveolar air CO 2 concentration (F CO 2 ). Increase in alveolar ventilation, which defines the state of hyperventilation, results in reduction of alveolar F CO 2 and therefore reduction in alveolar and arterial P co 2 . A schematic demonstration of F CO 2 -P co 2 relationship is seen in Fig 1. Thus, primary hyperventilation results in a reduction in alveolar P co 2 and consequential reduction in arterial P co 2 -the state of respiratory alkalosis. Hyperventilation. —The term "hyperventilation" should not be used to describe an accelerated rate of respiration (tachypnea), since such does not necessarily result in an increase in alveolar ventilation. Furthermore,