Carlo Unverzagt
2018; Wiley; Volume: 57; Issue: 29 Linguagem: Italiano
10.1002/anie.201802018
ISSN1521-3773
Tópico(s)Chemical Synthesis and Analysis
ResumoAngewandte Chemie International EditionVolume 57, Issue 29 p. 8813-8813 Author ProfileFree Access Carlo Unverzagt First published: 06 March 2018 https://doi.org/10.1002/anie.201802018AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “My science ‘heroes’ are Emil Fischer and Robert Koch. In the future I see myself growing wine in a sunny country ...” This and more about Carlo Unverzagt can be found on page 8813. Carlo Unverzagt The author presented on this page has published his 10th article since 2007 in Angewandte Chemie: “Breaking the Limits in Analyzing Carbohydrate Recognition by NMR Spectroscopy: Resolving Branch-Selective Interaction of a Tetra-Antennary N-Glycan with Lectins”: A. Canales, I. Boos, L. Perkams, L. Karst, T. Luber, T. Karagiannis, G. Domínguez, F. J. Cañada, J. Pérez-Castells, D. Häussinger, C. Unverzagt, J. Jiménez-Barbero, Angew. Chem. Int. Ed. 2017, 56, 14987; Angew. Chem. 2017, 129, 15183. Date of birth: November 28, 1958 Position: Chair of Bioorganic Chemistry, University of Bayreuth E-mail: carlo.unverzagt@uni-bayreuth.de Homepage: http://www.boc.uni-bayreuth.de/de/index.html Education: 1984 Undergraduate degree in chemistry, University of Mainz 1988 PhD supervised by Prof. Horst Kunz, University of Mainz 1988–1990 Postdoc with Prof. James C. Paulson, University of California, Los Angeles Awards: 1997 Carl Duisberg Memorial Prize, GDCh; 2010 Max Bergmann Medal, Max-Bergmann Kreis; 2017 Emil Fischer Award, European Carbohydrate Organization Current research interests: Chemoenzymatic synthesis of N-glycans, glycopeptides, glycoproteins, glycosyltransferases, glycobiology Hobbies: Off-piste skiing, water sports, exploring remote places My science “heroes” are Emil Fischer and Robert Koch. In the future I see myself growing wine in a sunny country. What I appreciate most about my friends is that sometimes they follow me even to the wildest places. My favorite musician is Fela Kuti. My favorite book is Water Music by T. C. Boyle. The natural talent I would like to be gifted with is the ability to get up early. When I was eighteen I wanted to be either a chemist (plan A) or a car mechanic (plan B). If I could be described as an animal it would be probably a sloth. My favorite drink is a strong red wine from anywhere in the world. My first experiment was the charring of sugar over a flame and lighting the fumes, as suggested in my first chemistry set. In a spare hour, I like to browse the newspaper looking for difficult sudokus or str8ts. I get (the best) advice from my senior colleagues and my wife. I advise my students to believe in their results. My favorite way to spend a holiday is close to any type of water (liquid or solid). My 5 top papers: 1“Semisynthesis of a Homogeneous Glycoprotein Enzyme: Ribonuclease C: Part 1”: C. Piontek, P. Ring, O. Harjes, C. Heinlein, S. Mezzato, N. Lombana, C. Pöhner, M. Püttner, D. Varón Silva, A. Martin, F. X. Schmid, C. Unverzagt, Angew. Chem. Int. Ed. 2009, 48, 1936; Angew. Chem. 2009, 121, 1968. (At first we thought it was going to be a walk in the park …) 2“Semisynthesis of a Homogeneous Glycoprotein Enzyme: Ribonuclease C: Part 2”: C. Piontek, D. Varón Silva, C. Heinlein, C. Pöhner, S. Mezzato, P. Ring, A. Martin, F. X. Schmid, C. Unverzagt, Angew. Chem. Int. Ed. 2009, 48, 1941; Angew. Chem. 2009, 121, 1974. (… However, it took a good decade to obtain and assemble all the required building blocks.) 3“Convergent Solid-Phase Synthesis of N-Glycopeptides Facilitated by Pseudoprolines at Consensus-Sequence Ser/Thr Residues”: V. Ullmann, M. Rädisch, I. Boos, J. Freund, C. Pöhner, S. Schwarzinger, C. Unverzagt, Angew. Chem. Int. Ed. 2012, 51, 11566; Angew. Chem. 2012, 124, 11734. (A long-sought reliable version of the Lansbury aspartylation was discovered in parallel with the Danishefky lab.) 4“Semisynthesis of Biologically Active Glycoforms of the Human Cytokine Interleukin 6 ”: A. Reif, S. Siebenhaar, A. Tröster, M. Schmälzlein, C. Lechner, P. Velisetty, K. Gottwald, C. Pöhner, I. Boos, V. Schubert, S. Rose-John, C. Unverzagt, Angew. Chem. Int. Ed. 2014, 53, 12125; Angew. Chem. 2014, 126, 12321. (This robust and flexible synthesis puts together a series of key developments ranging from the two-intein system to the use of latent thioesters.) 5“Highly Efficient Synthesis of Multiantennary Bisected N-glycans Based on Imidates”: M. Mönnich et al., Angew. Chem. Int. Ed. 2016, 55, 10487; Angew. Chem. 2016, 128, 10643. (With the right protecting-group pattern, unprecedented yields of the target products were obtained in a one-pot protocol.) Volume57, Issue29July 16, 2018Pages 8813-8813 ReferencesRelatedInformation
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