Fragrance contact dermatitis: a worldwide multicenter investigation (Part II)
2001; Wiley; Volume: 44; Issue: 6 Linguagem: Inglês
10.1034/j.1600-0536.2001.044006344.x
ISSN1600-0536
AutoresWalter G. Larsen, Hideo Nakayama, Torkil Fischer, Peter Elsner, Peter J. Frosch, Desmond Burrows, William P. Jordan, S. Shaw, John Wilkinson, James G. Marks, Makoto Sugawara, Marc Nethercott, James R. Nethercott,
Tópico(s)Allergic Rhinitis and Sensitization
ResumoThe purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 178 patients were evaluated in 8 centers worldwide with a fragrance mix (FM) and 20 other fragrance materials. Reaction to the fragrance mixture (FM) occurred in 78.7% of the subjects. Substances reacting at a rate of 2% or higher included jasmine absolute, geranium oil bourbon, l‐citronellol, spearmint oil, 1,3,4,6,7,8‐hexahydro‐4,6,6,7,8,8‐hexamethylcyclopenta‐γ‐2‐benzopyran, omega‐6‐hexadecenlactone, dimethyltetrahydrobenzaldehyde (isomer mixture), and α‐amylcinnamaldehyde. These chemicals should be furthur evaluated to corroborate their allergenicity. We are constantly looking for new fragrance allergens to extend the diagnostic capability of the fragrance mix (FM).
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