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The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation: Nurses Group - Poster Session

2018; Springer Nature; Volume: 53; Issue: S1 Linguagem: Inglês

10.1038/s41409-018-0322-2

1476-5365

Denise Wareham, Shirley Hudson, M. Ellis, Lara Rowley, Daja Barton, Erwin T. Janssen, Jessy Lardon, Jo Dierick, Pierre Zachée, Ka Wu, L. Katzir, Rasha Ashkar, Orna Ben, Gila Hyams, Tsila Zuckerman, Johan Lasse, Jørn Thue, Yngvar Kristiansen, Tobias Fløisand, Dominique Issarni, Steven Le Gouill, Efstathia Sarla, Konstantinos Gkontopoulos, Konstantinos Gkirkas, Panagiotis Tsirigotis, Laura Orlando, Francesca Patriarca, Stefano Botti, Iris Agreiter, Francesca Bonifazi, Nicola Mordini, Attilio Bondanza, Roberto Crocchiolo, Gianpaolo Gargiulo, Dawn Collier, George Trandafir, Laura Tipler, Wai Keong Wong, Annabel McMillan, Hebah Ali,

Polyomavirus and related diseases

Background: Sibling donors remain an important source of haematopoietic stem cells for allogeneic transplantation.Family dynamics are both complex and diverse and we must be mindful of this when considering potential sibling donors (PSDs).Methods: In Oxford, we have developed a donor-centered protocol that supports and respects the privacy of PSDs whilst recognising their freedom of choice and maintaining the JACIE Standards.The protocol was developed in response to a PSD complaint.Results: Initially, the patient is asked to identify and give permission for all or selected siblings to be approached.He/ she provides contact information and is asked to inform the PSD(s) that they will be contacted by the Oxford BMT team.All PSD receive written information about the donation process before the HLA tissue typing samples are taken.The process is flexible and recognises that not all PSD live local to the patient and some may live abroad.Local PSD have samples taken on site in Oxford, those who live outside the local area are sent postage pre-paid sample packs to have samples taken at their GP surgery and PSD who live abroad are asked to have samples taken and processed locally then reported to Oxford.HLA matching reports are issued by Transplant Immunology Oxford and they alert the BMT Administrator and she generates the appropriate letter(s) for donor(s) and patient from templates.All reports and letters are reviewed by a clinician before they are signed and posted.Where there is more than one sibling tissue typed, the reports are posted to each sibling at the same time.The letter to the patient is posted two days later than the sibling donor(s) letters.This ensures that matched and non-matched sibling donor(s) receive their results before the patient, allowing them time to consider their options and discuss with the BMT team if necessary.To maintain efficiency, the majority of communication is by letter but PSDs are directed to a Blood and Marrow Transplant (BMT) Nurse Coordinator if further discussion is required.The whole process is managed by the BMT Administrator, who plays a key role in ensuring accurate documentation, the provision of information, and sample collection.Conclusions: In our experience this protocol-based approach to PSD HLA tissue typing is beneficial to both patient and PSD.We believe that a positive donor experience relies on a well-coordinated and collaborative approach to the process.