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Amyotrophic Lateral Sclerosis

2017; Massachusetts Medical Society; Volume: 377; Issue: 2 Linguagem: Inglês

10.1056/nejmra1603471

1533-4406

Robert H. Brown, Ammar Al‐Chalabi,

Neurological diseases and metabolism

Progress has been made in understanding the genetic defects and the pathophysiology of this crippling motor neuron disease (commonly called Lou Gehrig’s disease). However, this information has not yet led to a successful intervention that alters the course of the disease.