Portal de Periódicos da CAPES

Topical Minoxidil in the Treatment of Male Erectile Dysfunction

1994; Lippincott Williams & Wilkins; Volume: 151; Issue: 5 Linguagem: Inglês

10.1016/s0022-5347(17)35217-5

1527-3792

Sidney B. Radomski, Sender Herschorn, Satish Rangaswamy,

Sexual function and dysfunction studies

No AccessJournal of Urology1 May 1994Topical Minoxidil in the Treatment of Male Erectile Dysfunction S.B. Radomski, S. Herschorn, and S. Rangaswamy S.B. RadomskiS.B. Radomski , S. HerschornS. Herschorn , and S. RangaswamyS. Rangaswamy View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)35217-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Topically applied 2% minoxidil solution has been reported to increase diameter, rigidity and arterial flow to the penis. As a result it has been suggested as a possible treatment for erectile dysfunction. A total of 21 patients received 2% minoxidil for treatment of erectile dysfunction with instructions to apply 1 cc of the solution slowly over the glans penis 20 minutes before intercourse. Average patient age was 52.5 years (range 29 to 65 years). The etiology of the impotence was neurogenic in 8 patients, vascular in 7, psychogenic in 4 and other causes in 2. Two patients also had clinical evidence of venous incompetence and 4 were diabetics. One patient with psychogenic impotence noticed improvement in the duration of erection but no increase in rigidity or size after minoxidil application. One patient with impotence after excision of a Peyronie’s plaque reported a rigid erection adequate for intercourse after using minoxidil. This patient subsequently was able to achieve erections without using minoxidil. The remaining 19 patients had no improvement in erectile rigidity or the ability to obtain or maintain an erection. One patient did notice some mild burning on the glans penis after applying the minoxidil. No other side effects were noted in any patient. These results indicate that 2% topical minoxidil solution is not effective when applied to the penis in the treatment of erectile dysfunction. It is possible that a higher concentration, a different delivery medium or a different chemical composition may yield better results. © 1994 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByKim E and McVary K (2018) Topical Prostaglandin-E1 for the Treatment of Erectile DysfunctionJournal of Urology, VOL. 153, NO. 6, (1828-1830), Online publication date: 1-Jun-1995. Volume 151Issue 5May 1994Page: 1225-1226 Advertisement Copyright & Permissions© 1994 by The American Urological Association Education and Research, Inc.Keywordsdrug therapypenile erectionminoxidilimpotenceMetricsAuthor Information S.B. Radomski More articles by this author S. Herschorn More articles by this author S. Rangaswamy More articles by this author Expand All Advertisement PDF DownloadLoading ...