Produção Nacional
Picobirnavirus
2020; Springer Nature; Linguagem: Inglês
10.1007/978-981-15-2651-0_13
ISSN2662-4354
AutoresNaveen Kumar, Joana D’ Arc Pereira Mascarenhas, Souvik Ghosh, Gisela Masachessi, Renato da Silva Bandeira, Silvia Nates, Kuldeep Dhama, Raj Kumar Singh, Yashpal Singh Malik,
Tópico(s)Viral Infections and Immunology Research
ResumoPicobirnaviruses (PBVs) recently occupied a place in the list of enteric viruses and are highly versatile due to their huge genetic diversity and wide host range. PBVs are small, non-enveloped viruses carrying a bi-segmented double-stranded RNA genome and have been placed within a new family 'Picobirnaviridae'. Nevertheless, PBVs have been detected primarily from the faeces of many host species, these viruses have also been reported in the respiratory tract of pigs and plasma of horses that needs further investigation for their inhabitant behaviour. Based on the available information, PBVs may be considered as opportunistic enteric pathogens; however, prokaryotic ribosomal binding motifs have been identified in many PBV gene segments, indicating that these may be prokaryotic viruses. Though PBVs may have an ambiguous clinical implication, they might pose a potential public health concern. Because of lack of suitable animal model/cell lines, there remains an uncertainty on the pathogenesis, persistence, and evolution of PBVs. The control of PBVs largely depends on the non-vaccine approach.
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