Portal de Periódicos da CAPES

Asymmetric Total Synthesis of Soraphen A: A Flexible Alkyne Strategy

2009; Wiley; Volume: 121; Issue: 30 Linguagem: Inglês

10.1002/ange.200901907

1521-3757

Barry M. Trost, Joshua D. Sieber, Wei Qian, Rajiv Dhawan, Zachary T. Ball,

Chemical synthesis and alkaloids

Wandelbare Dreifachbindung: Die Alkingruppe kann sowohl als Nucleophil wie auch als Elektrophil wirken, je nachdem, welchen Metallkatalysator man zur Aktivierung einsetzt. Dieser doppelsinnige Charakter der Alkingruppe wurde in der Totalsynthese des Naturstoffs Soraphen A genutzt (siehe Retrosynthese; PMB=para-Methoxybenzyl, TBS=tert-Butyldimethylsilyl). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.