Antiviral Fluorenone Derivatives from Arundina gramnifolia
2013; ASIAN PUBLICATION CORPORATION; Volume: 25; Issue: 17 Linguagem: Inglês
10.14233/ajchem.2013.15052
ISSN0975-427X
AutoresDe‐Yun Niu, Jing-Mei Han, Wei-Song Kong, Zhu-Wen Cui, Qiu‐Fen Hu, Xuemei Gao,
Tópico(s)Ginseng Biological Effects and Applications
ResumoA new fluorenone derivative, gramniphenol H (1), together with four known fluorenone derivatives (2-5) were isolated from the whole plant of Arundina gramnifolia. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compound 1 was tested for its cytotoxicity against five human tumor cell lines and it shows modest cytotoxicity against PC3 and SHSY5Y cell with IC50 values of 6.18 and 4.25 μM, respectively.
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