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Scientific Opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite (coated granulated preparation), based on a dossier submitted by Doxal Italia S.p.A

2015; Wiley; Volume: 13; Issue: 11 Linguagem: Inglês

10.2903/j.efsa.2015.4271

1831-4732

Heavy Metal Exposure and Toxicity

EFSA JournalVolume 13, Issue 11 4271 OpinionOpen Access Scientific Opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite (coated granulated preparation), based on a dossier submitted by Doxal Italia S.p.A EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Search for more papers by this author EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Search for more papers by this author First published: 10 November 2015 https://doi.org/10.2903/j.efsa.2015.4271Citations: 3 Panel members: Gabriele Aquilina, Vasileios Bampidis, Maria de Lourdes Bastos, Georges Bories, Andrew Chesson, Pier Sandro Cocconcelli, Gerhard Flachowsky, Jürgen Gropp, Boris Kolar, Maryline Kouba, Secundino López Puente, Marta López-Alonso, Alberto Mantovani, Baltasar Mayo, Fernando Ramos, Guido Rychen, Maria Saarela, Roberto Edoardo Villa, Robert John Wallace and Pieter Wester. Correspondence: feedap@efsa.europa.eu Acknowledgement: The Panel wishes to thank the members of the Working Group on Trace Elements, including Noël Dierick, Mikolaj Antoni Gralak, Christer Hogstrand, Lubomir Leng and Johannes Westendorf, for the preparatory work on this scientific opinion. Adoption date: 20 October 2015 Published date: 10 November 2015 Question number: EFSA-Q-2014-00508 On request from: European Commission AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Selenium is a trace element that is essential for vertebrates and involved in a series of vital metabolic functions. The additive, a coated granulated preparation of sodium selenite, consists of carrier granules to which the active compound, sodium selenite, is fixed using filming agents; it is manufactured with different selenium contents. Sodium selenite is considered to be a safe source of selenium for all animal species/categories, also when applied in coated granulated preparations. Based on extensive published literature data, the use of sodium selenite as a source of selenium in animal nutrition is considered to be safe for the consumer, provided that the total maximum authorised content of selenium in complete feed is respected. No concerns would arise from inhalation of selenium during the handling of the coated granulated preparation of sodium selenite owing to the very low estimated exposure. The coated granulated preparation of sodium selenite is considered to be an irritant to the skin, eyes and the respiratory system, and a skin sensitizer. Systemic exposure to selenium could result from dermal contact, particularly when cutaneous absorption of sodium selenite might be facilitated by skin damage; any dermal contact with the additive should be avoided. The use of sodium selenite in animal nutrition up to the maximum authorised content in feed would not raise concerns regarding the soil compartment, the ground or surface water. Concerning the marine sediments, given standard aquaculture practices and the low potential maximum concentration of selenium from fish feeds, any impact on the environment is unlikely. 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