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The Use of Alpha‐adrenergic Blockers in Benign Prostatic Obstruction

1976; Wiley; Volume: 48; Issue: 3 Linguagem: Inglês

10.1111/j.1464-410x.1976.tb10214.x

1365-2176

Marco Caine, Alphonse Pfau, S. Perlberg,

Prostate Cancer Diagnosis and Treatment

Summary As a result of previous in‐vitro studies on the a‐adrenergic receptor activity of the human prostate and prostatic capsule a trial was made of a‐adrenergic blockers for the relief of obstructive prostatic symptoms. Considerable benefit was obtained in several groups of patients, as demonstrated either by the relief or prevention of complete retention, or by diminution in residual urine or improvement in urinary flow‐rate recordings. A number of illustrative cases are described, and the indications for the use of this treatment are suggested. It is emphasised that this treatment provides symptomatic relief only, and in no sense purports to be a treatment of the enlarged prostate itself.