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Diagnostic Value of Preoperative Haemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score in Predicting Tumour Budding in Colorectal Cancer

2022; Volume: 32; Issue: 06 Linguagem: Inglês

10.29271/jcpsp.2022.06.751

1681-7168

Uğur Topal, Serkan Güler, Zafer Teke, Erdal Karaköse, İdris Kurtuluş, Hasan Bektaş,

Prostate Cancer Treatment and Research

To investigate the value of preoperative haemoglobin, albumin, lymphocyte, and platelet (HALP) score in predicting tumour budding in colorectal carcinoma.Observational study.University of Health Sciences, Başakşehir Çam and Sakura City Hospital İstanbul/Turkey, between May 2020 and May 2021.The colorectal cancer patients who underwent surgery were divided into two groups according to the presence or absence of tumour budding. A total of 110 patients were included in the study, and there were 31 patients in group 1 and 79 patients in group 2. The predictive value of the HALP score in predicting tumour budding at the determined cut-off point was evaluated.The mean HALP score was similar in both groups (p=0.459). The rate of lymphovascular invasion was higher in group 2 (p=0.002), and T3 and T4 tumours were more common in group 2 (p 31.6 predicted the presence of tumour budding with a sensitivity of 70.89% and a specificity of 48.39%.The presence of tumour budding is associated with aggressive phenotypic features in colorectal carcinoma. The preoperative prediction of tumour budding can serve as a guide in the development of individualised therapy plans. The HALP score was associated with the presence of intermediate or high degree of tumour budding.Colorectal cancer, Tumor, Pathology, Hemoglobin, Albumin.