Portal de Periódicos da CAPES

Artigo Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

Neuroinformatics Insights towards Multiple Neurosyphilis Complications

2022; Multidisciplinary Digital Publishing Institute; Volume: 1; Issue: 1 Linguagem: Inglês

10.3390/venereology1010010

2674-0710

Arun Kumar Jaiswal, Syed Babar Jamal, Lucas Gabriel Rodrigues Gomes, Rodrigo Profeta, Helioswilton Sales‐Campos, Carlo José Freire Oliveira, Flávia Figueira Aburjaile, Sandeep Tiwari, Debmalya Barh, Marcos Silva, Siomar de Castro Soares, Vasco Azevedo,

Authorship Attribution and Profiling

Treponema pallidum subspecies pallidum causes syphilis, a sexually transmitted disease that infects more than 2.1 million pregnant women every year. Due to its maximum death rates and augmented risk of human immunodeficiency virus (HIV) infection, the disease is still a matter of debate in many low- and high-income countries. The infection has three stages that lead to several complications if left untreated and can lead to many tertiary complications in the brain, eyes, ears, heart, and pregnancy. Neurosyphilis is also known as the clinical result of infection of the central nervous system by Treponema pallidum subspecies pallidum. It can evolve at any time and from any stage of syphilis exposure. This review briefly explains the severe and multiple neurosyphilitic complications and recently identified cases related to neurosyphilis. We also explained computational neuroscience, neuroinformatics, and in silico models and techniques based on artificial intelligence and other computational and mathematical methods. These techniques have already been applied to several neurological and psychological brain complications and can be applied to neurosyphilis to better understand the persistence of the disease related to the brain that causes neurosyphilis.