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Incidence of Intussusception in Bamako, Mali, Before and After the Introduction of Rotavirus Vaccine

2022; Oxford University Press; Volume: 11; Issue: 9 Linguagem: Inglês

10.1093/jpids/piac044

2048-7207

Anna Roose, Adama Mamby Keita, Milagritos D. Tapia, Samba O. Sow, T. Christopher Mast, Karen L. Kotloff,

Gastrointestinal disorders and treatments

Pentavalent rotavirus vaccine has been associated with a small increase in intussusception, but pre- and post-introduction data are lacking in many low-resource settings. Using chart review and prospective surveillance data, intussusception incidence was estimated in Bamako, Mali. The mean annual intussusception incidence post-introduction was not significantly different from that of pre-introduction.