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BIBTEX RIS

The BCL ‐2 family member BID plays a role during embryonic development in addition to its BH3 ‐only protein function by acting in parallel to BAX , BAK and BOK

2022; Springer Nature; Volume: 41; Issue: 15 Linguagem: Inglês

10.15252/embj.2021110300

ISSN

1460-2075

Autores

Francine S Ke, Steven Holloway, Rachel T. Uren, Agnes W. Wong, Melissa H. Little, Ruth M. Kluck, Anne K. Voss, Andreas Strasser,

Tópico(s)

Ubiquitin and proteasome pathways

Resumo

The intrinsic apoptosis pathway, regulated by the BCL-2 protein family, is essential for embryonic development. Using mice lacking all known apoptosis effectors, BAX, BAK and BOK, we have previously defined the processes during development that require apoptosis. Rare Bok

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