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Supplementation of diet with Brazil nut modulates body composition, bone parameters, and lipid peroxidation in Wistar rats
2022; Wiley; Volume: 46; Issue: 10 Linguagem: Inglês
10.1111/jfbc.14294
ISSN1745-4514
AutoresNathália da Silva Costa, Patrícia Pereira Almeida, Beatriz Oliveira Da Cruz, Michele Lima Brito, Johnatas Maldonado‐Campos, Ágatha Cristie Menezes, Mariana Sarto Figueiredo, D’Angelo Carlo Magliano, Aline D’Ávila Pereira, Milena Barcza Stockler‐Pinto,
Tópico(s)Diet and metabolism studies
ResumoJournal of Food BiochemistryVolume 46, Issue 10 e14294 ORIGINAL ARTICLE Supplementation of diet with Brazil nut modulates body composition, bone parameters, and lipid peroxidation in Wistar rats Nathalia da Silva Costa, Corresponding Author Nathalia da Silva Costa [email protected] orcid.org/0000-0003-2660-1800 Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Correspondence Nathalia da Silva Costa, Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Rua Mário Santos Braga 30, Niterói, RJ 24020-140, Brazil. Email: [email protected] Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing - original draft, Writing - review & editingSearch for more papers by this authorPatricia Pereira Almeida, Patricia Pereira Almeida Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Writing - review & editingSearch for more papers by this authorBeatriz Oliveira Da Cruz, Beatriz Oliveira Da Cruz orcid.org/0000-0002-3169-9315 Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Data curation, Investigation, Writing - review & editingSearch for more papers by this authorMichele Lima Brito, Michele Lima Brito Nutrition Graduation, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Investigation, Writing - review & editingSearch for more papers by this authorJohnatas Maldonado-Campos, Johnatas Maldonado-Campos Biomedicine Graduation, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Investigation, Writing - review & editingSearch for more papers by this authorAgatha Cristie Menezes, Agatha Cristie Menezes Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Investigation, Writing - review & editingSearch for more papers by this authorMariana Sarto Figueiredo, Mariana Sarto Figueiredo Nutrition Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Resources, Writing - review & editingSearch for more papers by this authorD' Angelo Carlo Magliano, D' Angelo Carlo Magliano Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Methodology, Resources, Writing - review & editingSearch for more papers by this authorAline D'Avila Pereira, Aline D'Avila Pereira Nutrition Department, Vassouras University, Maricá, Brazil Contribution: Data curation, Investigation, Methodology, Writing - review & editingSearch for more papers by this authorMilena Barcza Stockler-Pinto, Milena Barcza Stockler-Pinto Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Nutrition Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing - review & editingSearch for more papers by this author Nathalia da Silva Costa, Corresponding Author Nathalia da Silva Costa [email protected] orcid.org/0000-0003-2660-1800 Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Correspondence Nathalia da Silva Costa, Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Rua Mário Santos Braga 30, Niterói, RJ 24020-140, Brazil. Email: [email protected] Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing - original draft, Writing - review & editingSearch for more papers by this authorPatricia Pereira Almeida, Patricia Pereira Almeida Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Writing - review & editingSearch for more papers by this authorBeatriz Oliveira Da Cruz, Beatriz Oliveira Da Cruz orcid.org/0000-0002-3169-9315 Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Data curation, Investigation, Writing - review & editingSearch for more papers by this authorMichele Lima Brito, Michele Lima Brito Nutrition Graduation, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Investigation, Writing - review & editingSearch for more papers by this authorJohnatas Maldonado-Campos, Johnatas Maldonado-Campos Biomedicine Graduation, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Investigation, Writing - review & editingSearch for more papers by this authorAgatha Cristie Menezes, Agatha Cristie Menezes Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Investigation, Writing - review & editingSearch for more papers by this authorMariana Sarto Figueiredo, Mariana Sarto Figueiredo Nutrition Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Resources, Writing - review & editingSearch for more papers by this authorD' Angelo Carlo Magliano, D' Angelo Carlo Magliano Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Methodology, Resources, Writing - review & editingSearch for more papers by this authorAline D'Avila Pereira, Aline D'Avila Pereira Nutrition Department, Vassouras University, Maricá, Brazil Contribution: Data curation, Investigation, Methodology, Writing - review & editingSearch for more papers by this authorMilena Barcza Stockler-Pinto, Milena Barcza Stockler-Pinto Cardiovascular Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Nutrition Sciences Graduation Program, Fluminense Federal University (UFF), Niterói, Brazil Contribution: Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing - review & editingSearch for more papers by this author First published: 28 June 2022 https://doi.org/10.1111/jfbc.14294Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Oxidative stress, adipose tissue, and bone compartments can be disturbed in chronic diseases. Non-pharmacological strategies, such as Brazil nuts (BNs), can improve these parameters. This study evaluated the effects of BN supplementation at different concentrations on body composition, lipid profile, and peroxidation in healthy rats. Male Wistar rats were divided into three groups: control (CT), Brazil nut 5% (BN5), and Brazil nut 10% (BN10) groups. Body composition, brown adipose tissue (BAT), plasma lipid peroxidation, and lipid profile were evaluated in the three groups. The BN5 group showed an improvement in all bone parameters compared with that of the CT group (p < .0001). The BN5 and BN10 groups showed reduced plasma lipid peroxidation compared with that of the CT group (p = .0009), whereas the BN10 group presented lower BAT lipid peroxidation than that of the other groups (p = .01). High-density lipoprotein-cholesterol (HDL-c) levels were higher in the BN5 group than in the CT group (p = .01). Conclusively, the use of BNs in a controlled manner promoted improvement in bone parameters, HDL-c levels, and lipid peroxidation in healthy rats. Practical applications Nuts has been included in the diet because of their versatility, acceptance, and easy access. Among them, Brazil nut (BN) is considered one of the major known food sources of selenium as well as a source of fibers, unsaturated fatty acids, and phenolic compounds. Studies have shown that BN supplementation is effective in reducing oxidative stress, inflammation, lipid peroxidation, and selenium deficiency when used as a non-pharmacological strategy in experimental models of chronic diseases and in clinical trials. The present study showed that controlled administration of BN improved bone parameters, high-density lipoprotein-cholesterol levels, and lipid peroxidation in healthy rats. 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