Artigo Acesso aberto Revisado por pares

Association between peripheral inflammation and free-water imaging in Major Depressive Disorder before and after ketamine treatment – A pilot study

2022; Elsevier BV; Volume: 314; Linguagem: Inglês

10.1016/j.jad.2022.06.043

ISSN

1573-2517

Autores

Mina Langhein, Johanna Seitz‐Holland, Amanda E. Lyall, Ofer Pasternak, Natalia Chunga, Suheyla Cetin-Karayumak, Antoni Kubicki, Christoph Mulert, Randall Espinoza, Katherine L. Narr, Marek Kubicki,

Tópico(s)

Functional Brain Connectivity Studies

Resumo

Alterations in the peripheral inflammatory profile and white matter (WM) deterioration are frequent in Major Depressive Disorder (MDD). The present study applies free-water imaging to investigate the relationship between altered peripheral inflammation and WM microstructure and their predictive value in determining response to ketamine treatment in MDD.

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