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Comparing the values of anti-TPO and IL-17 among patients with thyroid disorders and comparing them with healthy controls in Ramadi City

2022; Linguagem: Inglês

10.53730/ijhs.v6ns5.9188

2550-6978

Rashied Mohammed Rashied, Ali M. Sameen, Ibraheem Abdulnabi Shabeeb,

Biomarkers in Disease Mechanisms

Even though most thyroid subjects are undiagnosed due to nonspecific symptoms, universal screening for thyroid disease is not recommended for the general population. In this study, our motive is to compare thyroid autoantibody anti-TPO and IL-17 in addition to traditional thyroid markers TSH, T4, and T3 between two patients' groups (patients with hypothyroidism (TSH) > 6 mIU/L and patients with hyperthyroidism TSH between 0.3 and 6 mIU/L) with a control group. Here a total of 45 subjects were divided into three groups, the first group consisted of 15 patients with hyperthyroidism. The second group consisted of 15 individuals with hypothyroidism, and the control group consisted of 15 healthy individuals. According to our results, an increase in TPO values was observed in all study groups, and the highest increase was recorded in the hyperthyroidism (386.672±116.924), and with regard to interleukin-17 values, a high value was observed in patients with hyperthyroidism (38.1033±5.44) compared to other groups.