Artigo Acesso aberto Revisado por pares

Alteration of gut microbiota in high‐fat diet‐induced obese mice using carnosic acid from rosemary

2022; Wiley; Volume: 10; Issue: 7 Linguagem: Inglês

10.1002/fsn3.2841

ISSN

2048-7177

Autores

Xuan He, Man Zhang, Shu‐Ting Li, Xinyu Li, Qingrong Huang, Kun Zhang, Xi Zheng, Xue‐Tao Xu, Deng‐Gao Zhao, Yan‐Yan Ma,

Tópico(s)

Biochemical Analysis and Sensing Techniques

Resumo

(rosemary) is widely used as a food ingredient. Rosemary extract (containing 40% carnosic acid) exhibited potent antiobesity activity. However, the relationship between carnosic acid (CA) and changes in the gut microbiota of high-fat diet (HFD)-induced obese mice has not been fully investigated. C57BL/6 mice were fed a normal diet, an HFD, or an HFD containing 0.1% or 0.2% CA for 10 weeks. CA exhibited promising antiobesity effects and caused marked alterations in the gut microbiota of HFD-induced obese mice. CA caused the prevalence of probiotics and functional bacteria, including

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