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Thyroid Function in 509 Premature Newborns Below 31 Weeks of Gestational Age: Evaluation and Follow-up

2022; Galenos Yayinevi; Volume: 14; Issue: 4 Linguagem: Inglês

10.4274/jcrpe.galenos.2022.2022-2-1

1308-5735

Ariadna Campos-Martorell, Alicia Montaner Ramón, Karla Narváez Barros, José Luis Marín Soria, Rosa Maria López Galera, Diego Yeste, María Clemente León,

Neonatal Respiratory Health Research

What is already known on this topic?Preterm and low birth weight (LBW) newborns are at risk of thyroid dysfunction during a critical period for neurodevelopment and this dysfunction can be missed in the congenital hypothyroidism screening program performed in whole-blood.The utility of a second screening, its optimal timing and the need of levothyroxine (LT4) still remain subjects for debate. What this study adds?This study included a large number of preterms and their follow up.This protocol was able to detect thyroid dysfunction in neonates who were not identified by the current program based on thyroid stimulating hormone determination in whole-blood.Most cases of thyroid dysfunction resolve spontaneously in a few months, but in some cases LT4 could be needed.