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Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup

2022; Elsevier BV; Volume: 23; Issue: 8 Linguagem: Inglês

10.1016/s1470-2045(22)00139-5

1474-5488

Ignace Vergote, Antonio González‐Martín, Domenica Lorusso, Charlie Gourley, Mansoor Raza Mirza, Jean‐Emmanuel Kurtz, Aikou Okamoto, Kathleen N. Moore, Frédéric Kridelka, Iain A. McNeish, Alexander Reuß, Bénédicte Votan, Andreas du Bois, Sven� Mahner, I. L. Ray-Coquard, Elise C. Kohn, Jonathan S. Berek, David S.P. Tan, Nicoletta Colombo, Rongyu Zang, Nicole Concin, Dearbhaile M. O’Donnell, Alejandro Rauh-Hain, C. Simon Herrington, Christian Marth, Andrés Poveda, Keiichi Fujiwara, Gavin Stuart, Amit M. Oza, Michael A. Bookman, Sven� Mahner, Alexander Reuß, Andreas du Bois, Christoph Grimm, Christian Marth, Regina Berger, Nicole Concin, Ting‐Chang Chang, Kazunori Ochiai, Val Gebski, Alison Davis, Philip Beale, Ignace Vergote, Frédéric Kridelka, Hannelore Denys, Vincent Vandecaveye, Francisco José Cândido dos Reis, Maria Del Pilar Estevez Diz, Gavin Stuart, Helen Mackay, Mark S. Carey, David Cibula, Pavel Dundr, Oliver Dorigo, Jonathan S. Berek, Dearbhaile M. O’Donnell, Feras Abu Saadeh, Ingrid Boere, Christianne Lok, Pluvio Coronado, Nelleke Ottevanger, David S.P. Tan, Joseph Ng, Antonio González‐Martín, Ana Oaknin, Andrés Poveda, Alejandro Perez Fidalgo, Alejandro Rauh-Hain, Karen H. Lu, Carlos López-Zavala, Eva María Gómez-García, I. L. Ray-Coquard, Xavier Paolettí, Jean‐Emmanuel Kurtz, Florence Joly, Bénédicte Votan, Michael A. Bookman, Kathleen N. Moore, Rebecca C. Arend, Keiichi Fujiwara, Hiroyuki Fujiwara, Kosei Hasegawa, Ilan Bruchim, Dalia Tsoref, Katsutoshi Oda, Aikou Okamoto, Takayuki Enomoto, Dayana Michel, Hee‐Seung Kim, Jung‐Yun Lee, Asima Mukhopadhyay, Dionyssios Katsaros, Nicoletta Colombo, Sandro Pignata, Domenica Lorusso, Giovanni Scambia, Elise C. Kohn, Jungmin Lee, Iain A. McNeish, Shibani Nicum, Laura Farrelly, Jalid Sehouli, Maren Keller, Elena Ioana Braicu, Line Bjørge, Mansoor Raza Mirza, Annika Auranen, Stephen Welch, Amit M. Oza, Viola Heinzelmann, Charlie Gourley, Patricia Roxburgh, C. Simon Herrington, Rosalind Glasspool, Rongyu Zang, Jianqing Zhu,

Cancer Genomics and Diagnostics

The Gynecologic Cancer InterGroup (GCIG) sixth Ovarian Cancer Conference on Clinical Research was held virtually in October, 2021, following published consensus guidelines. The goal of the consensus meeting was to achieve harmonisation on the design elements of upcoming trials in ovarian cancer, to select important questions for future study, and to identify unmet needs. All 33 GCIG member groups participated in the development, refinement, and adoption of 20 statements within four topic groups on clinical research in ovarian cancer including first line treatment, recurrent disease, disease subgroups, and future trials. Unanimous consensus was obtained for 14 of 20 statements, with greater than 90% concordance in the remaining six statements. The high acceptance rate following active deliberation among the GCIG groups confirmed that a consensus process could be applied in a virtual setting. Together with detailed categorisation of unmet needs, these consensus statements will promote the harmonisation of international clinical research in ovarian cancer.