
Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments
2022; American Chemical Society; Volume: 56; Issue: 16 Linguagem: Inglês
10.1021/acs.est.2c02896
ISSN1520-5851
AutoresEvgenios Agathokleous, Damià Barceló, Michael Aschner, Ricardo Antunes Azevedo, Prosun Bhattacharya, David Costantini, G. Christopher Cutler, Alessandra De Marco, Anca Oana Docea, José G. Dórea, Stephen O. Duke, Thomas Efferth, Despo Fatta‐Kassinos, Vasileios Fotopoulos, Antonio Ginebreda, R. N. C. Guedes, A. Wallace Hayes, Ivo Iavicoli, Olga‐Ioanna Kalantzi, Takayoshi Koike, Demetrios Kouretas, Manish Kumar, José E. Manautou, Michael N. Moore, Elena Paoletti, Josep Peñuelas, Yolanda Picó, Rüssel J. Reiter, Ramin Rezaee, Jörg Rinklebe, Teresa Rocha‐Santos, Pierre Sicard, Christian Sonne, Christopher M. Teaf, Aristidis Tsatsakis, Constantine Vardavas, Wenjie Wang, Eddy Y. Zeng, Edward J. Calabrese,
Tópico(s)Pesticide Exposure and Toxicity
ResumoADVERTISEMENT RETURN TO ARTICLES ASAPPREVViewpointNEXTRethinking Subthreshold Effects in Regulatory Chemical Risk AssessmentsEvgenios Agathokleous*Evgenios AgathokleousCollaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters (CIC-FEMD), Nanjing University of Information Science & Technology, Nanjing 210044, Jiangsu ChinaResearch Center for Global Changes and Ecosystem Carbon Sequestration & Mitigation, School of Applied Meteorology, Nanjing University of Information Science & Technology, Nanjing 210044, Jiangsu China*Email: [email protected]More by Evgenios AgathokleousView Biographyhttps://orcid.org/0000-0002-0058-4857, Damià BarcelóDamià BarcelóInstitute of Environmental Assessment and Water Research, IDAEA-CSIC; Barcelona 08034, SpainCatalan Institute for Water Research, ICRA-CERCA; Girona 17003, SpainMore by Damià Barcelóhttps://orcid.org/0000-0002-8873-0491, Michael AschnerMichael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine; Bronx, New York 10461, United StatesMore by Michael Aschnerhttps://orcid.org/0000-0002-2619-1656, Ricardo Antunes AzevedoRicardo Antunes AzevedoDepartamento de Genética, Escola Superior de Agricultura "Luiz de Queiroz"/Universidade de São Paulo (ESALQ/USP); São Paulo CEP 13418-900, BrazilMore by Ricardo Antunes Azevedo, Prosun BhattacharyaProsun BhattacharyaKTH-international Groundwater Arsenic Research Group, Department of Sustainable Development, Environmental Science and Engineering, KTH Royal Institute of Technology; Stockholm SE-100 44, SwedenMore by Prosun Bhattacharyahttps://orcid.org/0000-0003-4350-9950, David CostantiniDavid CostantiniUnité Physiologie Moléculaire et Adaptation (PhyMA), UMR 7221 Muséum National d'Histoire Naturelle; CNRS, 7 Rue Cuvier, 75005 Paris, FranceMore by David Costantinihttps://orcid.org/0000-0002-8140-8790, G. Christopher CutlerG. Christopher CutlerDepartment of Plant, Food, and Environmental Sciences, Agricultural Campus, Dalhousie University; Truro, Nova Scotia B2N 5E3, CanadaMore by G. Christopher Cutler, Alessandra De MarcoAlessandra De MarcoENEA, CR Casaccia, SSPT-PVS; Rome 00123, ItalyMore by Alessandra De Marcohttps://orcid.org/0000-0001-7200-2257, Anca Oana DoceaAnca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova; Craiova 200349, RomaniaMore by Anca Oana Docea, José G. DóreaJosé G. DóreaFaculdade de Ciências da Saúde, Universidade de Brasília; Brasília 70919-970, BrazilMore by José G. Dórea, Stephen O. DukeStephen O. DukeNational Center for Natural Products Research, School of Pharmacy, University of Mississippi; Mississippi 38677, United StatesMore by Stephen O. Dukehttps://orcid.org/0000-0001-7210-5168, Thomas EfferthThomas EfferthJohannes Gutenberg University, Institute of Pharmaceutical and Biomedical Sciences, Department of Pharmaceutical Biology; Mainz 55128, GermanyMore by Thomas Efferth, Despo Fatta-KassinosDespo Fatta-KassinosDepartment of Civil and Environmental Engineering and Nireas-International Water Research Centre, School of Engineering, University of Cyprus; P.O. Box 20537, Nicosia 1678, CyprusMore by Despo Fatta-Kassinos, Vasileios FotopoulosVasileios FotopoulosDepartment of Agricultural Sciences, Biotechnology and Food Science, Cyprus University of Technology; Lemesos 3603, CyprusMore by Vasileios Fotopouloshttps://orcid.org/0000-0003-1205-2070, Antonio GinebredaAntonio GinebredaEnvironmental Chemistry, IDAEA-CSIC, c/Jordi Girona 18-26, Barcelona 08034, SpainMore by Antonio Ginebreda, Raul Narciso C. GuedesRaul Narciso C. GuedesDepartamento de Entomologia, Universidade Federal de Viçosa;Viçosa, Minas Gerais 36570-900, BrazilMore by Raul Narciso C. Guedes, A. Wallace HayesA. Wallace HayesCenter for Environmental/Occupational Risk Analysis & Management, University of South Florida, College of Public Health; Tampa, Florida 33612, United StatesMichigan State University; East Lansing, Michigan 48824, United StatesMore by A. Wallace Hayes, Ivo IavicoliIvo IavicoliDepartment of Public Health, Section of Occupational Medicine, University of Naples Federico II; Naples 80131, ItalyMore by Ivo Iavicolihttps://orcid.org/0000-0003-0444-3792, Olga-Ioanna KalantziOlga-Ioanna KalantziDepartment of Environment, University of the Aegean; Mytilene 81100, GreeceMore by Olga-Ioanna Kalantzihttps://orcid.org/0000-0002-0466-212X, Takayoshi KoikeTakayoshi KoikeResearch Faculty of Agriculture, Hokkaido University; Sapporo, Hokkaido 060-8589, JapanMore by Takayoshi Koike, Demetrios KouretasDemetrios KouretasDepartment of Biochemistry-Biotechnology, University of Thessaly, Larisa 41500, GreeceMore by Demetrios Kouretas, Manish KumarManish KumarSchool of Engineering, University of Petroleum and Energy Studies; Dehradun 248007, IndiaMore by Manish Kumar, José E. ManautouJosé E. ManautouPharmaceutical Science, University of Connecticut, Storrs, Connecticut 06269, United StatesMore by José E. Manautou, Michael N. MooreMichael N. MooreEuropean Centre for Environment & Human Health (ECEHH), University of Exeter Medical School, Knowledge Spa, Royal Cornwall Hospital; Truro TR1 3HD, U.K.Plymouth Marine Laboratory; Plymouth, Devon PL1 3DH, U.K.School of Biological & Marine Sciences, University of Plymouth; Plymouth PL 4 8AA, U.K.More by Michael N. Moore, Elena PaolettiElena PaolettiInstitute of Research on Terrestrial Ecosystems, National Research Council; Sesto Fiorentino 50019, ItalyMore by Elena Paoletti, Josep PeñuelasJosep PeñuelasCSIC, Global Ecology Unit CREAF-CSIC-UAB; Bellaterra, Catalonia 08193, SpainCREAF; Cerdanyola del Vallès, Catalonia 08193, SpainMore by Josep Peñuelas, Yolanda PicóYolanda PicóEnvironmental and Food Safety Research Group (SAMA-UV), Desertification Research Centre (CIDE), Universitat de València-CSIC-GV; Valencia 46113, SpainMore by Yolanda Picóhttps://orcid.org/0000-0002-9545-0965, Russel J. ReiterRussel J. ReiterDepartment of Cell Systems and Anatomy, Joe R. and Teresa Lozano Long School of Medicine, UT Health San Antonio; San Antonio, Texas 78229, United StatesMore by Russel J. Reiter, Ramin RezaeeRamin RezaeeInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences,Mashhad 91779-43335, IranApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad 91779-43335, IranMore by Ramin Rezaee, Jörg RinklebeJörg RinklebeUniversity of Wuppertal, School of Architecture and Civil Engineering, Institute of Foundation Engineering, Water, and Waste-Management, Laboratory of Soil, and Groundwater-Management; Wuppertal 42285, GermanyMore by Jörg Rinklebehttps://orcid.org/0000-0001-7404-1639, Teresa Rocha-SantosTeresa Rocha-SantosCentre for Environmental and Marine Studies (CESAM) & Department of Chemistry, University of Aveiro; Aveiro 3810-193, PortugalMore by Teresa Rocha-Santos, Pierre SicardPierre SicardARGANS, 260 route du Pin Montard, Biot 06410, FranceMore by Pierre Sicard, Christian SonneChristian SonneAarhus University, Department of Bioscience, Arctic Research Centre (ARC); Roskilde DK-4000, DenmarkHenan Province Engineering Research Center for Biomass Value-added Products, School of Forestry, Henan Agricultural University; Zhengzhou 450002, ChinaMore by Christian Sonnehttps://orcid.org/0000-0001-5723-5263, Christopher TeafChristopher TeafInstitute of Science & Public Affairs, Florida State University; Tallahassee, Florida 32306, United StatesMore by Christopher Teaf, Aristidis TsatsakisAristidis TsatsakisLaboratory of Toxicology, Medical School, University of Crete; Heraklion 71003, GreeceMore by Aristidis Tsatsakis, Alexander I. VardavasAlexander I. VardavasLaboratory of Toxicology, Medical School, University of Crete; Heraklion 71003, GreeceMore by Alexander I. Vardavas, Wenjie WangWenjie WangKey Laboratory of Forest Plant Ecology, Northeast Forestry University; Harbin 150040, ChinaNortheast Institute of Geography and Agroecology, Chinese Academy of Science; Changchun 130102, ChinaMore by Wenjie Wang, Eddy Y. ZengEddy Y. ZengGuangdong Key Laboratory of Environmental Pollution and Health, School of Environment, Jinan University; Guangzhou 511443, ChinaMore by Eddy Y. Zenghttps://orcid.org/0000-0002-0859-7572, and Edward J. CalabreseEdward J. CalabreseDepartment of Environmental Health Sciences, University of Massachusetts; Amherst, Massachusetts 01003, United StatesMore by Edward J. CalabreseCite this: Environ. Sci. Technol. 2022, XXXX, XXX, XXX-XXXPublication Date (Web):July 25, 2022Publication History Received24 April 2022Published online25 July 2022https://doi.org/10.1021/acs.est.2c02896© 2022 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views610Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. 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