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SUPERINFECTANT MICROORGANISMS FROM THE SUPRAGINGIVAL BIOFILM OF AN ONCOLOGY PATIENT

2022; Elsevier BV; Volume: 134; Issue: 3 Linguagem: Inglês

10.1016/j.oooo.2022.01.284

2212-4411

Gabrielly Braga Camargos De Almeida, Ananda Pereira Oliveira, Larissa Ramos De Almeida, Luana Maria Rosário Martins, Vinicius da Costa Vieira, Patrícia Leite Ribeiro, Viviane Almeida Sarmento,

Oral and Maxillofacial Pathology

Enterobacteria are superinfecting microorganisms, and their presence in the oral cavity is associated with increased mortality rates due to virulence factors. The objective of the study was to report a case of oral infection by enterobacteria. A 29-year-old man diagnosed with acute promyelocytic leukemia and under the PETHEMA protocol required dental evaluation during a chemotherapy regimen. On dental physical examination, extraoral swelling was noted in the right hemiface, associated with a painful, purple-colored lesion in the marginal gingiva of tooth 48. Computed tomography did not show any alteration that could corroborate the diagnosis. Cultures from an oral swab were obtained from the injured region, and Klebsiella pneumoniae and Enterobacter sp. were detected. Mouthwash with 3% hydrogen peroxide was indicated to control the oral microbiota, associated with intravenous antibiotic therapy with meropenem, polymyxin, B, and tigecycline. Complete remission of the oral lesion was observed after 10 days of treatment. Enterobacteria are superinfecting microorganisms, and their presence in the oral cavity is associated with increased mortality rates due to virulence factors. The objective of the study was to report a case of oral infection by enterobacteria. A 29-year-old man diagnosed with acute promyelocytic leukemia and under the PETHEMA protocol required dental evaluation during a chemotherapy regimen. On dental physical examination, extraoral swelling was noted in the right hemiface, associated with a painful, purple-colored lesion in the marginal gingiva of tooth 48. Computed tomography did not show any alteration that could corroborate the diagnosis. Cultures from an oral swab were obtained from the injured region, and Klebsiella pneumoniae and Enterobacter sp. were detected. Mouthwash with 3% hydrogen peroxide was indicated to control the oral microbiota, associated with intravenous antibiotic therapy with meropenem, polymyxin, B, and tigecycline. Complete remission of the oral lesion was observed after 10 days of treatment.