Portal de Periódicos da CAPES

HAMARTOMATOUS TONGUE LESIONS IN PEDIATRIC PATIENTS: REPORT OF 8 CASES

2022; Elsevier BV; Volume: 134; Issue: 3 Linguagem: Inglês

10.1016/j.oooo.2022.01.220

2212-4411

Maria Eduarda Pérez‐de‐Oliveira, Liam Robinson, Willie F. P. van Heerden, José Narciso Rosa Assunção, Pablo Agustín Vargas,

Hedgehog Signaling Pathway Studies

A hamartoma is the proliferation of normal tissues that are considered endogenous to the site of occurrence. Hamartomas are rarely seen in the oral cavity. The aim of this study is to report clinicopathologic features of 8 additional tongue hamartoma cases in pediatric patients. Female patients outnumbered male patients by 1:6, and the age of patients ranged from 2 weeks to 4 years old. One case was associated with oral-facial-digital syndrome and another one with the presence of cleft palate and encephalocele. The most common histopathologic presentation was the presence of 4 concomitant components, including skeletal muscle, fat, salivary glands, nerves, and vessels. All cases were treated by surgical excision. Although hamartoma is rare, it must be including in differential diagnosis of masses located in tongues of pediatric patients. A hamartoma is the proliferation of normal tissues that are considered endogenous to the site of occurrence. Hamartomas are rarely seen in the oral cavity. The aim of this study is to report clinicopathologic features of 8 additional tongue hamartoma cases in pediatric patients. Female patients outnumbered male patients by 1:6, and the age of patients ranged from 2 weeks to 4 years old. One case was associated with oral-facial-digital syndrome and another one with the presence of cleft palate and encephalocele. The most common histopathologic presentation was the presence of 4 concomitant components, including skeletal muscle, fat, salivary glands, nerves, and vessels. All cases were treated by surgical excision. Although hamartoma is rare, it must be including in differential diagnosis of masses located in tongues of pediatric patients.