Produção Nacional
Revisado por pares
Three-Dimensional Printing and Its Potential to Develop Sensors for Cancer with Improved Performance
2022; Multidisciplinary Digital Publishing Institute; Volume: 12; Issue: 9 Linguagem: Inglês
10.3390/bios12090685
ISSN2079-6374
AutoresJoão Batista Maia Rocha Neto, Juliana Coatrini Soares, Guilherme Arthur Longhitano, Andrey Coatrini Soares, Hernandes F. Carvalho, Osvaldo N. Oliveira, Marisa Masumi Beppu, Jorge Vicente Lopes da Silva,
Tópico(s)Nanofabrication and Lithography Techniques
ResumoCancer is the second leading cause of death globally and early diagnosis is the best strategy to reduce mortality risk. Biosensors to detect cancer biomarkers are based on various principles of detection, including electrochemical, optical, electrical, and mechanical measurements. Despite the advances in the identification of biomarkers and the conventional 2D manufacturing processes, detection methods for cancers still require improvements in terms of selectivity and sensitivity, especially for point-of-care diagnosis. Three-dimensional printing may offer the features to produce complex geometries in the design of high-precision, low-cost sensors. Three-dimensional printing, also known as additive manufacturing, allows for the production of sensitive, user-friendly, and semi-automated sensors, whose composition, geometry, and functionality can be controlled. This paper reviews the recent use of 3D printing in biosensors for cancer diagnosis, highlighting the main advantages and advances achieved with this technology. Additionally, the challenges in 3D printing technology for the mass production of high-performance biosensors for cancer diagnosis are addressed.
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