Produção Nacional
Revisado por pares
The Effects of Ejaculation on Serum Prostate Specific Antigen
1996; Lippincott Williams & Wilkins; Volume: 155; Issue: 4 Linguagem: Inglês
10.1016/s0022-5347(01)66258-x
ISSN1527-3792
AutoresNelson Rodrígues Netto, Fábio Apuzzo, Enrico Andrade, Gelsio B. Srulzon, Pedro Luis Cortado, Marcelo Lopes de Lima,
Tópico(s)Urologic and reproductive health conditions
ResumoNo AccessJournal of UrologyClinical Urology: Original Article1 Apr 1996The Effects of Ejaculation on Serum Prostate Specific Antigen Nelson Rodrigues Netto, Fabio Apuzzo, Enrico de Andrade, Gelsio B. Srulzon, Pedro Luis Cortado, and Marcelo Lopes Lima Nelson Rodrigues NettoNelson Rodrigues Netto , Fabio ApuzzoFabio Apuzzo , Enrico de AndradeEnrico de Andrade , Gelsio B. SrulzonGelsio B. Srulzon , Pedro Luis CortadoPedro Luis Cortado , and Marcelo Lopes LimaMarcelo Lopes Lima View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66258-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated the correlation of prostate specific antigen (PSA) and ejaculation in patients with symptomatic benign prostatic hyperplasia and an active sexual life. Materials and Methods: In a study of 40 patients 50 to 60 years old (mean age 55) with prostatic symptoms serum PSA was evaluated before as well as 1 and 7 days after ejaculation. Due to the clinical significance of PSA in diagnosis and monitoring of prostate cancer, we included men at risk age and with an active sexual life. Results: The results were compared to those of a control group of 10 asymptomatic (without coitus) men 50 to 60 years old (mean age 55 years). There were no statistically significant differences in PSA levels before and after ejaculation or between the groups. These results suggested that there was no physiological relationship between ejaculation and PSA level. Conclusions: Based on our data we conclude that sexual activity does not preclude the use of PSA to screen men for prostatic cancer. References 1 : Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. New Engl. J. Med.1987; 317: 909. Google Scholar 2 : The effect of digital rectal examination on serum levels of prostatic-specific antigen. Arch. Path. Lab. Med.1988; 112: 1110. Google Scholar 3 : Serum prostatic specific antigen: in vitro stability and the effect of ultrasound rectal examination in vivo. Ann. Clin. Biochem.1987; 24: 206. Google Scholar 4 : Effects of rectal examination, prostatic massage, ultrasonography and needle biopsy on serum prostate specific antigen levels. J. Urol.1992; 147: 810. Link, Google Scholar 5 : Prostate specific antigen and prostatic acid phosphatase in the monitoring and staging of patients with prostatic cancer. J. Urol.1987; 138: 1181. Link, Google Scholar 6 : Tumour markers in prostatic carcinoma. A comparison of prostate-specific antigen with acid phosphatase. Brit. J. Urol.1987; 60: 69. Google Scholar 7 : Clinical use of prostate specific antigen in patients with prostate cancer. J. Urol.1989; 142: 1011. Link, Google Scholar 8 : Prostate-specific antigen: establishment of the reference range for clinically normal prostate gland and the effect of digital rectal examination, ejaculation, and time on serum concentrations. Prostate1992; 21: 99. Google Scholar 9 : The impact of ejaculation on serum prostate specific antigen. J. Urol.1993; 150: 895. Abstract, Google Scholar 10 : The impact of ejaculation on serum PSA. J. Urol., part 21995; 153: 464A. abstract 941. Google Scholar 11 : Keratin immunoreactivity in the benign and neoplastic human prostate. Cancer Res.1985; 45: 3663. Google Scholar 12 : Issues in assessment of PSA immunoassays. Urol. Clin. N. Amer.1993; 20: 607. Google Scholar 13 : Effect of digital rectal examination (and ejaculation) on serum prostate-specific antigen after twenty-four hours. A randomized, prospective study. Urolog.1993; 41: 111. Google Scholar Division of Urology, Hospital Beneficencia Portuguesa, Sao Paulo, Brazil© 1996 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 155Issue 4April 1996Page: 1329-1331 Advertisement Copyright & Permissions© 1996 by American Urological Association, Inc.MetricsAuthor Information Nelson Rodrigues Netto More articles by this author Fabio Apuzzo More articles by this author Enrico de Andrade More articles by this author Gelsio B. Srulzon More articles by this author Pedro Luis Cortado More articles by this author Marcelo Lopes Lima More articles by this author Expand All Advertisement PDF DownloadLoading ...
Referência(s)