Artigo Acesso aberto Revisado por pares

Circulating tumor DNA monitoring for early recurrence detection in epithelial ovarian cancer

2022; Elsevier BV; Volume: 167; Issue: 2 Linguagem: Inglês

10.1016/j.ygyno.2022.09.004

ISSN

1095-6859

Autores

June Y. Hou, Jocelyn Chapman, Ekaterina Kalashnikova, William E. Pierson, Karen Smith‐McCune, Geovanni Pineda, Reena M. Vattakalam, Alexandra Ross, Meredith Mills, Carlos J. Suarez, Tracy C. Davis, Robert P. Edwards, M.M. Boisen, Sarah Sawyer, Hsin-Ta Wu, Scott Dashner, Vasily N. Aushev, Giby V. George, Meenakshi Malhotra, Bernhard Zimmermann, Himanshu Sethi, Adam C. ElNaggar, Alexey Aleshin, James M. Ford,

Tópico(s)

PARP inhibition in cancer therapy

Resumo

Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. We examined the utility of circulating tumor DNA (ctDNA) as a prognostic biomarker for EOC by assessing its relationship with patient outcome and CA-125, pre-surgically and during post-treatment surveillance.

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