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The Functional Consequences of Structural Changes in the Airways

2003; Elsevier BV; Volume: 123; Issue: 3 Linguagem: Inglês

10.1016/s0012-3692(15)35205-3

1931-3543

Lu Wang, Brent E. McParland, Peter D. Paré,

Respiratory and Cough-Related Research

Over the last decade, there has been increasing recognition that structural change (ie, remodeling) in the airways of asthmatic subjects is a characteristic feature of the disease and may have important functional implications. Remodeling can be defined as changes in the composition, content, and organization of the cellular and molecular constituents of the airway wall.