Artigo Acesso aberto Revisado por pares

The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022

2022; Nature Portfolio; Volume: 13; Issue: 1 Linguagem: Inglês

10.1038/s41467-022-33549-6

ISSN

2041-1723

Autores

Saranya Sridhar, Roman M. Chicz, William H. Warren, Jim Tartaglia, Stephen J. Savarino, Sanjay Gurunathan, Jean‐François Toussaint,

Tópico(s)

Viral gastroenteritis research and epidemiology

Resumo

Currently approved COVID vaccines are designed using the spike antigen derived from the ancestral strain, but health authorities are recommending changes to the vaccine strain to combat emerging variants. The goal is to ensure that next generation vaccines can tackle multiple variants of concern including the most prevalent variant for the coming season. We here discuss recent preclinical and clinical data on COVID vaccine antigens that are potential candidates for an updated vaccine.

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