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Increased risk of cardiac dysfunction after anthracyclines in girls

1993; Alan R. Liss, Inc.; Volume: 21; Issue: 7 Linguagem: Inglês

10.1002/mpo.2950210704

1096-911X

Jeffrey H. Silber, Regina I. Jakacki, Ranae L. Larsen, Joel W. Goldwein, Gerald Barber,

Chemotherapy-induced organ toxicity mitigation

Medical and Pediatric OncologyVolume 21, Issue 7 p. 477-479 Article Increased risk of cardiac dysfunction after anthracyclines in girls Dr. Jeffrey H. Silber MD, PhD, Corresponding Author Dr. Jeffrey H. Silber MD, PhD Division of Oncology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaDivision of Oncology, Rm. 9093, Children's Hospital of Philadelphia 34th & Civic Center Blvd., Philadelphia, PA 19104Search for more papers by this authorDr. Regina I. Jakacki MD, Dr. Regina I. Jakacki MD Division of Oncology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorDr. Ranae L. Larsen MD, Dr. Ranae L. Larsen MD Division Cardiology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorJoel W. Goldwein MD, Joel W. Goldwein MD Department of Radiation Oncology, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorGerald Barber MD, Gerald Barber MD Division Cardiology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this author Dr. Jeffrey H. Silber MD, PhD, Corresponding Author Dr. Jeffrey H. Silber MD, PhD Division of Oncology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaDivision of Oncology, Rm. 9093, Children's Hospital of Philadelphia 34th & Civic Center Blvd., Philadelphia, PA 19104Search for more papers by this authorDr. Regina I. Jakacki MD, Dr. Regina I. Jakacki MD Division of Oncology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorDr. Ranae L. Larsen MD, Dr. Ranae L. Larsen MD Division Cardiology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorJoel W. Goldwein MD, Joel W. Goldwein MD Department of Radiation Oncology, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorGerald Barber MD, Gerald Barber MD Division Cardiology, Children's Hospital of Philadelphia Department of Pediatrics, University of Pennsylvania School of Medicine and the Hospital of the University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this author First published: 1993 https://doi.org/10.1002/mpo.2950210704Citations: 112AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Steinherz L, Steinherz P, Tan C, Heller G, Murphy L: Cardiac toxicity 4 to 20 years after completing anthracycline therapy. JAMA 1991; 266: 1672–1677. 2 Lipshultz SE, Golan SD, Gelber RD, et al: Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood. N Engl J Med 324: 808–815, 1991. 3 Jakacki R, Goldwein J, Larsen R, Barber G, Silber JH: Cardiac dysfunction following spinal irradiation during childhood. J Clin Oncol 11: 1033–1038, 1993. 4 Green MV, Ostrow MG, Douglas MA et al: High temporal resolution ECG gated scintigraphic angiocardiography. J Nucl Med 16: 95, 1975. 5 Alexander J, Dainiak N, Berger HJ, et al: Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. 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Am J Cardiol 67: 309–312, 1991. 10 Triebwasser JH, Johnson RL, Burpo RP, et al: Noninvasive determination of cardiac output by a modified acetylene rebreathing procedure utilizing mass spectrometer measurements. Aviation Space Environ Med 48: 203–209, 1977. 11 Kallay MC, Hyde RW, Smith RJ, et al: Cardiac output by rebreathing in patients with cardiopulmonary diseases. J Appl Physiol 63: 201–210, 1987. 12 Silber JH, Jakacki R, Larsen R, Barber G: Forecasting exercise function after anthracyclines in childhood: The role of dose, age, and sex. In DM Green, GJ D'angio, JT Bricker (eds): " Cardiac Toxicity After Treatment for Childhood Cancer." New York: John Wiley and Sons, in press. 13 Sullivan MJ, Cobb FR, Higginbotham MB: Stroke volume increases by similar mechanisms during upright exercise in normal men and women. Am J Cardiol 67: 1405–1412, 1991. 14 Rodvold KA, Rushing DA, Tewksbury DA: Doxorubicin clearance in the obese. J Clin Oncol 6: 1321–1327, 1988. 15 Hrushesky JM, Darrell JF, Berestka JS, et al: Diminishment of respiratory sinus arrythmia forshadows doxorubicin-Induced car-Diomyopathy. Circulation 84: 697–707, 1991. 16 Silber JH, Jakacki R, Larson R, Barber G: Forcasting exercise function after anthracyclines in childhood: The role of dose, age, and sex. Proc ASCO 11: 370, 1992 (abstr 1280). Citing Literature Volume21, Issue71993Pages 477-479 ReferencesRelatedInformation