Zinc and Cutaneous Inflammation
1985; American Medical Association; Volume: 121; Issue: 8 Linguagem: Inglês
10.1001/archderm.1985.01660080039011
ISSN1538-3652
Autores Tópico(s)Oral Health Pathology and Treatment
ResumoZinc and other trace metals are important cofactors and modulators of many critical biologic functions in the states of both health and disease. The role of zinc in modulating the immune response and inflammation has posed many questions concerning the potential usefulness of trace metals in modulating inflammatory disease. 1 The descriptions of zinc deficiency in acrodermatitis enteropathica, 2 the correction of the clinical disease in patients with acrodermatitis enteropathica via zinc supplementation, 3 and the correlation of improvement with certain changes in immunologic variables 4 have focused our attention on the potential usefulness of trace metals in treating inflammatory cutaneous diseases. Previous reports about modulation of autoimmune disease by zinc depletion 5 and the treatment of acne, 6 and a report about dissecting cellulitis of the scalp reported in this issue of theArchives, 7 continue to stimulate our interest in the role of zinc in cutaneous inflammation and its
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