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High throughput millifluidics mixer with double triangle baffle for improvement of mixing performance and reduction of flow resistance designed by grey relational analysis

2022; Elsevier BV; Volume: 181; Linguagem: Inglês

10.1016/j.cep.2022.109166

1873-3204

Shuangfei Zhao, Yimin Wei, Pengjie Yu, Yingying Nie, Runze Hu, Wei He, Ning Zhu, Yuguang Li, Dong Ji, Kai Guo,

Microfluidic and Bio-sensing Technologies

• A new type of mixer with double triangle baffle is proposed. • A novel method is used to find the mixer with the best overall performance. • The mixer achieves high mixing performance and low flow resistance. • The optimal configuration of the mixer is scaled-up to centimeter level. To improve the mixing performance and reduce flow resistance, in this study, a novel mixer with double triangle baffles was designed and optimized by the combination of CFD simulation and grey relation analysis method. Mixing index and Poiseuille number were selected as two key indexes to evaluate the mixing performance and flow resistance of the mixer. The orthogonal experiment was conducted with selecting the aspect ratio of baffles ( α ), the thickness of baffles ( h ), the spacing between adjacent baffles ( c ) and the number of baffles ( d ) as design variables. Among all design variables, d has the greatest influence on the mixer performances. The results show that the optimized mixer has a maximum increase of 14.25% in mixing index and a maximum decrease in Poiseuille number of 60.02%. Finally, the optimal configuration was scaled-up to centimeter level, which makes the mixer have high mixing performance, low flow resistance and high throughput at the same time. All the findings provide useful references for high throughput mixer design and optimization.