Produção Nacional
Revisado por pares
First Genomic Evidence of a Henipa-like Virus in Brazil
2022; Multidisciplinary Digital Publishing Institute; Volume: 14; Issue: 10 Linguagem: Inglês
10.3390/v14102167
ISSN1999-4915
AutoresLeonardo Henrique Almeida Hernández, Thito Yan Bezerra da Paz, Sandro Patroca da Silva, Fábio S. da Silva, Bruno de Cássio Veloso de Barros, Bruno Tardelli Diniz Nunes, Lívia Medeiros Neves Casseb, Daniele Barbosa de Almeida Medeiros, Pedro Fernando da Costa Vasconcelos, Ana Cecília Ribeiro Cruz,
Tópico(s)Vector-Borne Animal Diseases
ResumoThe viral genus Henipavirus includes two highly virulent zoonotic viruses of serious public health concern. Hendra henipavirus and Nipah henipavirus outbreaks are restricted to Australia and Southeast Asia, respectively. The Henipavirus genus comprises mostly bat-borne viruses, but exceptions have already been described as novel viruses with rodents and shrews as reservoir animals. In the Americas, scarce evidence supports the circulation of these viruses. In this communication, we report a novel henipa-like virus from opossums (Marmosa demerarae) from a forest fragment area in the Peixe-Boi municipality, Brazil, after which the virus was named the Peixe-Boi virus (PBV). The application of next-generation sequencing and metagenomic approach led us to discover the original evidence of a henipa-like virus genome in Brazil and South America and the original description of a henipa-like virus in marsupial species. These findings emphasize the importance of further studies to characterize PBV and clarify its ecology, impact on public health, and its relationship with didelphid marsupials and henipaviruses.
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