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Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease

2022; American Medical Association; Volume: 79; Issue: 12 Linguagem: Inglês

10.1001/jamaneurol.2022.3718

2168-6157

Kara Stevens, Siobhan Creanor, Alison Jeffery, Alan Whone, John Zajicek, Andy Foggo, Ben Jones, Rebecca Chapman, Laura Cocking, Jonny Wilks, Doug Webb, Camille Carroll, Jemma Inches, Donna Underwood, Julie Frost, Ali James, Christine Schofield, Rob S. James, Clare O’Reilly, Ray Sheridan, Sarah Statton, Anita Goff, Tamlyn Russell, Alison Whitcher, Sarah Craw, Alison Lewis, Rani Sophia, Khaled Amar, Rochelle Hernandez, Alison Pitcher, Samantha Carvey, Ruth Hamlin, Veronica Lyell, Louisa Aubry, Gillian Carey, Jan Coebergh, Idah Mojela, Sophie Molloy, Yolanda Berceruelo Bergaz, Bintou Camera, Philip Campbell, Huw R. Morris, Tinashe Samakomva, Anette Schrag, Sarah Fuller, Anjum Misbahuddin, Laura C. Parker, Elisa Visentin, Stephanie Gallehawk, Jacqueline Rudd, Sudhir Kumar Singh, Sarsha Wilson, Julie Creven, Yvonne Croucher, Susan Tluk, Paul Watts, Simone Hargreaves, Danielle Johnson, Lucy Worboys, Paul Worth, Judith Brooke, Christopher Kobylecki, Victoria A. Parker, Linda L. Johnson, Rosane Joseph, Julie Melville, Jason Raw, Janice Birt, Marianne Hare, Saifuddin Shaik, Jane Alty, Jeremy Cosgrove, David J. Burn, Angela Green, Ann P. McNichol, Nicola Pavese, Helen Pilkington, Maria Price, Kathryn Walker, К. Ray Chaudhuri, Aleksandra Podlewska, Prashanth Reddy, Dhaval Trivedi, Oliver Bandmann, R. T. Clegg, Grace Cole, Anna Emery, Václav Dostál, Jodie Graham, Jocelyn Keshet-Price, Godwin Mamutse, Alex Miller-Fik, Alison Wiltshire, Catherine Wright, Kathryn Dixon, Ahmed H. Abdelhafiz, Joanne Rose,

Ginkgo biloba and Cashew Applications

Current treatments manage symptoms of Parkinson disease (PD), but no known treatment slows disease progression. Preclinical and epidemiological studies support the potential use of statins as disease-modifying therapy.