Produção Nacional
Revisado por pares
Development of a new non invasive prognostic stroke scale (NIPSS) including triage elements for sleep apnea and peripheral artery disease
2022; Elsevier BV; Volume: 32; Issue: 1 Linguagem: Inglês
10.1016/j.jstrokecerebrovasdis.2022.106864
ISSN1532-8511
AutoresAlice Silva de Oliveira, Moises Correia Dantas, Pedro Antônio Pereira de Jesus, Daniel Santana Farias, Bruno Mota de Almeida, Caio Sales de Oliveira Santos, Caio Silveira Leite Alves Santos, Camila Rodrigues Blumetti, Carolina Dourado de Faria, Caroline de Carvalho Costa, Daniela Plácido Fernandes, Evelyn de Brito Nogueira, Gabriela de Queiroz Fonseca, Joao Pedro Miguez Pinto, Isabelle Jacqueline Weber Oliveira, Lara Santos Barcelos, Liz Ulm Ferreira Velloso, Marcio Jamerson Pinheiro Lucio, Milla Dantas Pimenta, Osvaldo Carlos Silva Leopoldino, Rafaella Cazé de Medeiros, Tairone Matos de Lima, Tiffany Almeida Santana, Vinicius Ruas Lacerda, Yasmin de Fátima Vilasboas Alcantara, Jamary Oliveira‐Filho,
Tópico(s)Cerebrovascular and Carotid Artery Diseases
ResumoAlthough sleep apnea and peripheral artery disease are prognostic factors for stroke, their added benefit in the acute stage to further prognosticate strokes has not been evaluated.We tested the accuracy in the acute stroke stage of a novel score called the Non-Invasive Prognostic Stroke Scale (NIPSS).Prospective cohort with imaging-confirmed ischemic stroke. Clinical data, sleep apnea risk score (STOPBANG) and blood pressure measures were collected at baseline. Primary outcome was the 90-day modified Rankin Scale (mRS), with poor outcome defined as mRS 3-6. Area under the ROC curve (AUC) was calculated for NIPSS and compared to six other stroke prognostic scores in our cohort: SPAN-100 index, S-SMART, SOAR, ASTRAL, THRIVE, and Dutch Stroke scores.We enrolled 386 participants. After 90 days, there were 56% with poor outcome, more frequently older, female predominant and with higher admission National Institute of Health Stroke Scale (NIHSS). Four variables remained significantly associated with primary endpoint in the multivariable model: age (OR 1.87), NIHSS (OR 7.08), STOPBANG category (OR 1.61), and ankle-braquial index (OR 2.11). NIPSS AUC was 0.86 (0.82-0.89); 0.83 (0.79-0.87) with bootstrapping. When compared to the other scores, NIPSS, ASTRAL, S-SMART and DUTCH scores had good abilities in predicting poor outcome, with AUC of 0.86, 0.86, 0.83 and 0.82, respectively. THRIVE, SOAR and SPAN-100 scores were fairly predictive.Non-invasive and easily acquired emergency room data can predict clinical outcome after stroke. NIPSS performed equal to or better than other prognostic stroke scales.
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