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Anti-microbial Peptides against Methicillin-resistant Staphylococcus aureus: Promising Therapeutics

2022; Bentham Science Publishers; Volume: 24; Issue: 2 Linguagem: Inglês

10.2174/1389203724666221216115850

1875-5550

Ravi Ranjan Kumar Niraj, Vinay Sharma, Priyanka Sinoliya, Pooran Singh Solanki, Sakshi Piplani,

Biochemical and Structural Characterization

Multidrug-resistant (MDR) methicillin-resistant Staphylococcus aureus (MRSA) has become a prime health concern globally. These bacteria are found in hospital areas where they are regularly dealing with antibiotics. This brings many possibilities for its mutation, so drug resistance occurs.Nowadays, these nosocomial MRSA strains spread into the community and live stocks. Resistance in Staphylococcus aureus is due to mutations in their genetic elements.As the bacteria become resistant to antibiotics, new approaches like antimicrobial peptides (AMPs) play a vital role and are more efficacious, economical, time, and energy saviours.Machine learning approaches of Artificial Intelligence are the in silico technique which has their importance in better prediction, analysis, and fetching of important details regarding AMPs.Anti-microbial peptides could be the next-generation solution to combat drug resistance among Superbugs. For better prediction and analysis, implementing the in silico technique is beneficial for fast and more accurate results.