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Acute TMS/fMRI response explains offline TMS network effects – An interleaved TMS-fMRI study

2022; Elsevier BV; Volume: 267; Linguagem: Inglês

10.1016/j.neuroimage.2022.119833

1095-9572

Martin Tik, Michael Woletz, Anna‐Lisa Schuler, Maria Vasileiadi, Robin Cash, Andrew Zalesky, Claus Lamm, Christian Windischberger,

Functional Brain Connectivity Studies

Transcranial magnetic stimulation (TMS) is an FDA-approved therapeutic option for treatment resistant depression. However, exact mechanisms-of-action are not fully understood and individual responses are variable. Moreover, although previously suggested, the exact network effects underlying TMS' efficacy are poorly understood as of today. Although, it is supposed that DLPFC stimulation indirectly modulates the sgACC, recent evidence is sparse.