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CorrespondenceExtramammary Paget disease in a patient with hidradenitis suppurativa

2022; Oxford University Press; Volume: 48; Issue: 4 Linguagem: Inglês

10.1093/ced/llac099

1365-2230

Conn McGrath, Roberto Corso, Andrew B. Williams, Nick Watkin, Eduardo Calonje, Ellie Rashidghamat, Helena Malhomme de la Roche,

Oral Health Pathology and Treatment

Dear Editor, Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma that usually affects areas with abundant apocrine glands, such as anogenital or axillary skin. It is classified into primary disease, adenocarcinoma of cutaneous origin, or secondary disease, an epidermotropic spread of an underlying malignancy. White women and Asian men are affected at disproportionally higher rates.1,2 Perianal involvement is present in 20% of cases and is the most common site affected in men.1,2 EMPD can appear similar to an inflammatory dermatosis and rates of misdiagnosis are high. To our knowledge, EMPD has never before been diagnosed in a patient with comorbid hidradenitis suppurativa (HS) or on adalimumab therapy. We present a case of EMPD diagnosed incidentally in excised skin from a patient who underwent surgical management of extensive HS of the groin. A 23-year-old man of Sri Lankan heritage, with Hurley stage III HS, was referred from our tertiary HS clinic for surgical management of his groin disease. He had significant disease with indurated plaques and actively discharging sinuses (Figure 1a).