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The Outcome of COVID-19 Infection on Kidney Transplantation Recipients in Southern Saudi Arabia: Single-Center Experience

2023; Elsevier BV; Volume: 55; Issue: 3 Linguagem: Inglês

10.1016/j.transproceed.2022.12.013

1873-2623

Hany M El Hennawy, Omar Safar, Adel Elatreisy, Abdullah S. Al Faifi, Osama Shalkamy, Sara Hadi, Mofareh Alqahtani, Sultan Ahmad Alkahtani, Faisal Saeed Alqahtani, Weam El Nazer, Eisa Al Atta, Asad Taha Ibrahim, Abdelaziz A. Abdelaziz, Naveed Mirza, Ahmed Mahedy, Nayana Mary Tom, Yahya Assiri, Ali Al Fageeh, Galal Elgamal, Ali Amer Al Shehri, Mohammad F. Zaitoun,

COVID-19 and healthcare impacts

To report the incidence, risk factors, and outcome of severe COVID-19 disease in kidney transplant recipients attending a Saudi hospital at a single center in the Kingdom of Saudi Arabia.A retrospective chart-based cohort study involving all kidney transplant recipients tested for COVID-19 in the Armed Forces Hospital Southern Region, KSA.Of 532 kidney transplant recipients who reported to the center, from March 2020 to June 2022, 180 were tested for COVID-19. Of these recipients, 31 (17%) tested positive. Among the 31 positive recipients, 11 were treated at home, 15 were admitted to the noncritical isolation ward, and 5 were admitted to the intensive care unit (ICU). Older age (P = .0001), higher body mass index (P = .0001), and history of hypertension (P = .0023) were more frequent in the COVID-19-positive recipients. Admission to the ICU was more frequent in older recipients (P = .0322) with a history of ischemic heart disease (P = .06) and higher creatinine baseline (P = .08) presenting with dyspnea (P = .0174), and acute allograft dysfunction (P = .002). In the ICU group, 4 (80%) patients required hemodialysis, and 4 (80%) died.Kidney transplant recipients with COVID-19 could have a higher risk for developing acute kidney injury, dialysis, and mortality than the general population. ICU admission and renal replacement therapy were more evident in older recipients with a history of ischemic heart disease, presenting with shortness of breath (P = .017) and a higher serum creatinine baseline. Acute allograft dysfunction was the independent predictor of mortality among patients admitted to the ICU.