Evaluation of the fish acute toxicity test for pesticide registration
2023; Elsevier BV; Volume: 139; Linguagem: Inglês
10.1016/j.yrtph.2023.105340
ISSN1096-0295
AutoresPatricia Ceger, David Allen, Amy Blankinship, Neepa Choksi, Amber B. Daniel, William P. Eckel, Jon Hamm, D. Ethan Harwood, Tamara M. Johnson, Nicole Kleinstreuer, Catherine S. Sprankle, James F. Truax, Michael Lowit,
Tópico(s)Pesticide Exposure and Toxicity
ResumoThe U.S. Environmental Protection Agency (USEPA) uses the in vivo fish acute toxicity test to assess potential risk of substances to non-target aquatic vertebrates. The test is typically conducted on a cold and a warm freshwater species and a saltwater species for a conventional pesticide registration, potentially requiring upwards of 200 or more fish. A retrospective data evaluation was conducted to explore the potential for using fewer fish species to support conventional pesticide risk assessments. Lethal concentration 50% (LC
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