Artigo Acesso aberto Revisado por pares

Evaluation of the fish acute toxicity test for pesticide registration

2023; Elsevier BV; Volume: 139; Linguagem: Inglês

10.1016/j.yrtph.2023.105340

ISSN

1096-0295

Autores

Patricia Ceger, David Allen, Amy Blankinship, Neepa Choksi, Amber B. Daniel, William P. Eckel, Jon Hamm, D. Ethan Harwood, Tamara M. Johnson, Nicole Kleinstreuer, Catherine S. Sprankle, James F. Truax, Michael Lowit,

Tópico(s)

Pesticide Exposure and Toxicity

Resumo

The U.S. Environmental Protection Agency (USEPA) uses the in vivo fish acute toxicity test to assess potential risk of substances to non-target aquatic vertebrates. The test is typically conducted on a cold and a warm freshwater species and a saltwater species for a conventional pesticide registration, potentially requiring upwards of 200 or more fish. A retrospective data evaluation was conducted to explore the potential for using fewer fish species to support conventional pesticide risk assessments. Lethal concentration 50% (LC

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