Artigo Acesso aberto Revisado por pares

Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal

2023; AOSIS; Volume: 24; Issue: 1 Linguagem: Inglês

10.4102/sajhivmed.v24i1.1458

ISSN

2078-6751

Autores

Sibongiseni Malinga, Aabida Khan, Moherndran Archary,

Tópico(s)

Acute Lymphoblastic Leukemia research

Resumo

We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adherence and close monitoring of treatment-experienced patients with virologic failure following switching to dolutegravir-based regimens.

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