Produção Nacional
Revisado por pares
Is There Any Relationship Between Chronic Urticaria, Its Severity and Alexithymia?
2023; Elsevier BV; Volume: 151; Issue: 2 Linguagem: Inglês
10.1016/j.jaci.2022.12.771
ISSN1097-6825
AutoresLuis Escalante, Iván Chérrez-Ojeda, Simon Francis Thomsen, Ana M. Giménez‐Arnau, Jennifer Astrup Sørensen, Kiran Godse, Carole Guillet, Astrid Karolina Maldonado Apolo, Gonzalo Chorzepa, Blanca María Morfín-Maciel, Jose Ignacio Larco Sousa, Erika De Arruda Chaves, Abhishek De, Daria Fomina, Anant Patil, Roberta Jardim Criado, Luís Felipe Ensina, Solange Oliveira Rodrigues Valle, Rosana Câmara Agondi, Herberto Chong Neto, Nelson Augusto Rosário Filho, German D. Ramón, Marco Faytong-Haro, Isabel Ogueta, Ivan Tinoco Moran, Jaime Cárdenas, Mariana Tinoco Chabla, Sandy Aguilar Gavilanes, Victor Estuardo Farinango Salazar, Silvio Duran Huacon, Pablo Maldonado Donoso, Nelson Vergara Muñoz, Johnny Gallardo Gallardo, Damelis Martinez Letterni, Karla Robles‐Velasco,
Tópico(s)Dermatology and Skin Diseases
ResumoIncreased attention is being paid to alexithymia in skin diseases, and has been described as a worrisome comorbidity. The goal of the cross-sectional study was to explore the relationship between chronic urticaria (CU) and its severity on alexithymia. Ordinal logistic regressions were used to predict CU in individuals with no alexithymia, possible alexithymia, or alexithymia. The model predicted TAS-20 based on UAS7 (Urticaria Activity Score), also controlling for gender, age, postsecondary education, marital status, cardiovascular, autoimmune, cancer, allergy, and mental comorbidities; diagnosis time; first- or second-generation antihistaminic medication use, omalizumab and corticoid use. 423 people from Ecuador, Peru, Chile, Argentina, Mexico, Peru, Brazil, Denmark, Germany, India, and Russia took part in this study, and 48.05% of them were men. The average age and disease years were 43.6 and 5.2. 42.08% of patients presented with alexithymia and 21.51% may have been affected (TAS-20). Patients with well-controlled CU had a considerably increased risk of developing alexithymia (OR=1.74) after adjusting for covariates. ORs were 2.08, 2.27, and 2.18 for mild, moderate, and severe CU, respectively. Our model results reveal that it is only necessary to present a controlled CU to have higher odds of alexithymia. After this point, patients with higher degrees of CU have similar odds of developing alexithymia (approximately double the odds as those with no CU). Other CU predictors (CU category and CUQ2OL) yielded similar results. Medical practitioners should be cautious about alexithymia when treating CU patients due its link with suicidal ideation, maladaptive coping strategies, and poor sleep.
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