Artigo Acesso aberto Produção Nacional Revisado por pares

Inhibition potential of Caryocar brasiliense on methicillin-resistant Staphylococcus pseudintermedius isolated from the ocular surface of dogs with ophthalmopathies

2023; UNIVERSIDADE FEDERAL DE MINAS GERAIS; Volume: 75; Issue: 1 Linguagem: Inglês

10.1590/1678-4162-12593

ISSN

1678-4162

Autores

Fábio Fernandes Bruno Filho, Wanessa Ferreira Ataíde, Ariel Eurides Stella, Sandra Aparecida Benite‐Ribeiro, Liliane Nebo, Andréia Vítor Couto do Amaral,

Tópico(s)

Phytochemistry and Bioactivity Studies

Resumo

ABSTRACT The indiscriminate use of antibiotics has contributed to the emergence of multiresistant bacteria. Faced with this, the search for antibiotics from plants has proven to be a promising alternative. The objective of this work was to isolate and identify Staphylococcus sp. resistant to methicillin of the ocular surface of dogs with ophthalmopathies and to evaluate its susceptibility to alcoholic extract of the bark and hexane extract of the pulp of Caryocar brasiliense. Biological material was collected from the ocular surface of 21 dogs presenting ophthalmopathies. We isolated 64 S. pseudintermedius, among these, 4 isolates were identified as methicillin-resistant S. pseudintermedius (MRSP). The alcoholic extract of C. brasiliense peel was able to inhibit the bacterial growth of MRSP isolates at a concentration of 2.2%. Thus, the extract from the C. brasiliense peel has antimicrobial potential and represents an alternative in the control of MRSP.

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