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Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19

2023; American Medical Association; Volume: 329; Issue: 11 Linguagem: Inglês

10.1001/jama.2023.1650

1538-3598

Susanna Naggie, David R. Boulware, Christopher J. Lindsell, Thomas G. Stewart, Alex Slandzicki, Stephen C. Lim, Jonathan B. Cohen, David Kavtaradze, Arch Amon, Ahab Gabriel, Nina T. Gentile, G. Michael Felker, Dushyantha Jayaweera, Matthew W. McCarthy, Mark Sulkowski, Russell L. Rothman, Sybil Wilson, Allison DeLong, April Remaly, Rhonda Wilder, Sean P. Collins, Sarah E. Dunsmore, Stacey J. Adam, Florence Thicklin, George J. Hanna, Adit A. Ginde, Mario Castro, Kathleen M. McTigue, Elizabeth Shenkman, Adrian F. Hernandez, William Vincent, Raina Vincent, Ray Bianchi, Jen Premas, Diana Cordero-Loperena, E. M. Rivera, Madhu Gupta, Greg Karawan, Carey Ziomek, Joseph Arena, Sonaly DeAlmeida, Soroush Ramin, Jaya Nataraj, Michael K. Paasche‐Orlow, Lori Henault, Katie Waite, David Miller, Ginger Brounce, Constance George-Adebayo, Adeolu Adebayo, Jessica Wallan, Claudia Vogel, Sebastian Munoz, Cassandra Watson, David Singleton, Maria Rivon, Amanda Sevier, Arnold Del Pilar, Amber Spangler, Sohail Rao, Luis Cantu, Arvind Krishna, Kathy Evans, Tylene Falkner, Brandi Kerr, Robert Spees, Mailyn Marta, Amanda Harrington, Rowena J Dolor, Madison Frazier, Lorraine Vergara, Jessica Wilson, Valencia Burruss, Terri Hurst, Igho Ofotokun, Pauline Rebolledo, Rajesh Prabhu, Krystal Klicka, Amber Lightfeather, Vicki James, Marcella Rogers, Pradeep Parihar, De'Ambra Torress, Chukwuemeka Oragwu, Ngozi Oguego, Rajesh Pillai, Mustafa Juma, Emad Ghaly, Dafer Al-Haddadin, Courtney Ramirez, Gammal Hassanien, Samah Ismail, Andrew Meltzer, Seamus Moran, Scott Brehaut, Angelina Roche, Manisha Mehta, Nicole Koppinger, Jose Baez, Ivone Pagan, Dallal Abdelsayed, Mina Aziz, Philip A. Robinson, Julie Nguyen, Victoria Pardue, Lisa Hammons, Juan Ruiz-Unger, Susan Gonzalez, Lionel Reyes, John J. Cienki, Gisselle Jimenez, Matthew Wong, Ying Yuan, Jenny Li, Jeremy Szeto, Lauren Stelmash, Daniel Haight, Deryl Lamb, Amron Harper, Nancy Pyram-Bernard, Arlen Quintero, Eftim Adhami, Josette Maria, Diksha Paudel, Oksana Raymond, Jeffrey Summers, Tammy Turner, Leslie Lenert, Sam Gallegos, Elizabeth Ann Szwast, Ahsan Abdulghani, Pravin Vasoya, Conrad Miller, Hawa Wiley, Nirav Shah, Tovah Klein, Julie Castex, Phillip Feliciano, Jacqueline Olivo, Marian Ghaly, Zainub Javed, Alexandra Nawrocki, Anthony G. Vecchiarelli, Nikki Vigil, Vijaya Cherukuri, Erica Burden, Dawn Linn, Laura Fisher, Vijay K. Patel, Praksha Patel, Yuti Patel, Leonard Ellison, Jeffrey Harrison, Binod Shah, Sugata Shah, Upinder Singh, Julia Donahue, Yasmin Jazayeri, Anita Gupta, N Chandrasekar, Beth Moritz, Tabitha Fortt, Anisa Fortt, Ingrid Jones-Ince, Alix McKee, Christy Schattinger, Jason Wilson, Brenda Farlow, Lillian Finlaw, Randall Richwine, Tearani Williams, Penny Paizer, Lisa Carson, Edward A. Michelson, Danielle Austin, Sangeeta Khetpal, Tiffany Cantrell, Drew Franklin, Karissa Marshall, Arvind Mahadevan, Madelyn Rosequist, Martin Gnoni, Crystal Daffner, Carla VandeWeerd, Mitchell Roberts, Mark D'Andrea, Wayne Swink, Margaret V. Powers‐Fletcher, Sylvere Mukunzi, Jamie Hensley, Brittney Manning, Carmen Isache, Jennifer Bowman, Angelique Callaghan-Brown, Taylor Scott, Tiffany Schwasinger‐Schmidt, Ashlie Cornejo, Maria Almanzar, Letty Ginsburg, Americo Hajaz, Carolyn T. Bramante, Matthew C. Robinson, Michelle Seithel, Akira Sekikawa, Emily Klawson, Luis Ostrosky, Virginia Umana, Thomas F. Patterson, Robin Tragus, Patrick E. H. Jackson, Caroline Hallowell, Heather M. Haughey, Bhavna Vaidya-Tank, Cameron Gould, Parul Goyal, Carly Gatewood, John Williamson, Hannah M. Seagle, Elizabeth Salsgiver, Eddie Armas, Jhonsai Cheng, Priscilla Huerta, Julia Garcia‐Diaz, David Aamodt, JaMario Ayers, Jess Collins, John Graves, James Grindstaff, Jessica Lai, Itzel Lopez, Jessica Marlin, Alyssa Merkel, Sam Nwosu, Savannah Obregon, Dirk Orozco, Yoli Perez-Torres, Nelson Prato, Colleen Ratcliff, Max Rhode, Jana Shirey-Rice, Krista Vermillion, Hsi-Nien Tan, Seibert Tregoning, Meghan Vance, Amber Vongsamphanh, Maria Weir, Nicole Zaleski, Samuel A. Bozzette, Gene Passamani,

Parasites and Host Interactions

It is unknown whether ivermectin, with a maximum targeted dose of 600 μg/kg, shortens symptom duration or prevents hospitalization among outpatients with mild to moderate COVID-19.