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HISTOLOGICAL EVALUATION OF THE TESTICULAR NUBBIN IN THE VANISHING TESTIS SYNDROME

1998; Lippincott Williams & Wilkins; Volume: 160; Issue: 3 Part 2 Linguagem: Inglês

10.1016/s0022-5347(01)62726-5

1527-3792

Marc Cendron, Alan R. Schned, Pamela Ellsworth,

Sperm and Testicular Function

No AccessJournal of UrologyTestes/Intersex1 Sep 1998HISTOLOGICAL EVALUATION OF THE TESTICULAR NUBBIN IN THE VANISHING TESTIS SYNDROME MARC CENDRON, ALAN R. SCHNED, and PAMELA I. ELLSWORTH MARC CENDRONMARC CENDRON , ALAN R. SCHNEDALAN R. SCHNED , and PAMELA I. ELLSWORTHPAMELA I. ELLSWORTH View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)62726-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We reviewed histopathological studies of the testicular nubbins associated with the vanishing testis syndrome, and determined whether surgical removal is indicated based on the histological findings. Materials and Methods: Between 1983 and 1997 a unilateral testicular nubbin consistent with a vanishing testis was excised in 29 patients an average of 28.6 months old. We retrospectively reviewed the gross pathology reports and microscopic slides, and prospectively performed histochemical stain analysis. Results: Gross evaluation of the specimens revealed an identifiable cord structure in the majority of cases with the vas deferens most commonly identified in 72.4%. No recognizable testicular elements were present in any nubbin. In 3 cases the original pathology report identified cells with features consistent with Leydig cells, which immunohistochemical staining revealed to be atrophied cremasteric muscle fibers. Conclusions: In this series testicular nubbins in vanishing testes contained no viable testicular tissue. Since the risk of testicular cancer in an undescended testis is 8 to 10% and the incidence of viable testicular tissue in these nubbins ranges from 0% in our series to 11% in others, there is only a 0 to 1.1% risk of testicular cancer in the nubbin. Thus, surgical removal may not be warranted. 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Google Scholar From the Departments of Surgery (Section of Urology) and Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire© 1998 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byWood H and Elder J (2018) Cryptorchidism and Testicular Cancer: Separating Fact From FictionJournal of Urology, VOL. 181, NO. 2, (452-461), Online publication date: 1-Feb-2009.Desireddi N, Liu D, Maizels M, Rigsby C, Casey J and Cheng E (2008) Magnetic Resonance Arteriography/Venography is Not Accurate to Structure Management of the Impalpable TestisJournal of Urology, VOL. 180, NO. 4S, (1805-1809), Online publication date: 1-Oct-2008.EGGENER S, LOTAN Y and CHENG E (2018) MAGNETIC RESONANCE ANGIOGRAPHY FOR THE NONPALPABLE TESTIS: A COST AND CANCER RISK ANALYSISJournal of Urology, VOL. 173, NO. 5, (1745-1750), Online publication date: 1-May-2005.RENZULLI J, SHETTY R, MANGRAY S, ANDERSON K, WEISS R and CALDAMONE A (2018) CLINICAL AND HISTOLOGICAL SIGNIFICANCE OF THE TESTICULAR REMNANT FOUND ON INGUINAL EXPLORATION AFTER DIAGNOSTIC LAPAROSCOPY IN THE ABSENCE OF A PATENT PROCESSUS VAGINALISJournal of Urology, VOL. 174, NO. 4 Part 2, (1584-1586), Online publication date: 1-Oct-2005.DE LUNA A, ORTENBERG J and CRAVER R (2018) Exploration for Testicular Remnants: Implications of Residual Seminiferous Tubules and Crossed Testicular EctopiaJournal of Urology, VOL. 169, NO. 4, (1486-1489), Online publication date: 1-Apr-2003.VAN SAVAGE J (2018) AVOIDANCE OF INGUINAL INCISION IN LAPAROSCOPICALLY CONFIRMED VANISHING TESTIS SYNDROMEJournal of Urology, VOL. 166, NO. 4, (1421-1424), Online publication date: 1-Oct-2001.YEUNG C, TAM Y, CHAN Y, LEE K and METREWELI C (2018) A NEW MANAGEMENT ALGORITHM FOR IMPALPABLE UNDESCENDED TESTIS WITH GADOLINIUM ENHANCED MAGNETIC RESONANCE ANGIOGRAPHYJournal of Urology, VOL. 162, NO. 3 Part 2, (998-1002), Online publication date: 1-Sep-1999. Volume 160Issue 3 Part 2September 1998Page: 1161-1163 Advertisement Copyright & Permissions© 1998 by American Urological Association, Inc.MetricsAuthor Information MARC CENDRON More articles by this author ALAN R. SCHNED More articles by this author PAMELA I. ELLSWORTH More articles by this author Expand All Advertisement PDF downloadLoading ...