Portal de Periódicos da CAPES

Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis

2023; Multidisciplinary Digital Publishing Institute; Volume: 16; Issue: 3 Linguagem: Inglês

10.3390/ph16030414

1424-8247

Noé Garín, Borja Zarate-Tamames, Laura Gras-Martín, Raimón Milà, Astrid Crespo‐Lessmann, Elena Curto, Marta Hernández, C. Mestres, Vicente Plaza,

Chronic Obstructive Pulmonary Disease (COPD) Research

We conducted a systematic review and meta-analysis to gain insight into the characteristics and clinical impact of electronic monitoring devices of inhalers (EMDs) and their clinical interventions in adult patients with asthma or COPD. The search included PubMed, Web of Science, Cochrane, Scopus and Embase databases, as well as official EMDs websites. We found eight observational studies and ten clinical trials, assessing a wide range of clinical outcomes. Results from the meta-analysis on adherence to inhalers in a period over three months were favourable in the EMD group (fixed effects model: SMD: 0.36 [0.25–0.48]; random effects model SMD: 0.41 [0.22–0.60]). An exploratory meta-analysis found an improvement in ACT score (fixed effect model SMD: 0.25 [0.11–0.39]; random effects model: SMD: 0.47 [−0.14–1.08]). Other clinical outcomes showed mixed results in the descriptive analyses. The findings of this review highlight the benefits of EMDs in the optimization of adherence to inhaled therapy as well as the potential interest in other clinical outcomes.