Revisão Acesso aberto Produção Nacional Revisado por pares

Influence of age, gender, previous SARS-CoV-2 infection, and pre-existing diseases in antibody response after COVID-19 vaccination: A review

2023; Elsevier BV; Volume: 156; Linguagem: Inglês

10.1016/j.molimm.2023.03.007

ISSN

1872-9142

Autores

Maria da Conceição Rodrigues Fernandes, Germana Silva Vasconcelos, Amanda Campelo Lima de Melo, Tamires Cardoso Matsui, Ludmilla Freire Caetano, Fernanda Montenegro de Carvalho Araújo, Marcela Helena Gambim Fonseca,

Tópico(s)

COVID-19 Clinical Research Studies

Resumo

Vaccines induce specific long-term immunological memory against pathogens, preventing the worsening of diseases. The COVID-19 health emergency has caused more than 6 million deaths and started a race for vaccine development. Antibody response to COVID-19 vaccines has been investigated primarily in healthcare workers. The heterogeneity of immune responses and the behavior of this response in particular groups were still very little explored. In this review, we discuss whether antibody responses after vaccination are influenced by age, gender, previous SARS-CoV-2 infection, or pre-existing diseases.

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