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Artigo Produção Nacional Revisado por pares

BIBTEX RIS

Epithelial salivary gland tumors in pediatric patients: An international collaborative study

2023; Elsevier BV; Volume: 168; Linguagem: Inglês

10.1016/j.ijporl.2023.111519

1872-8464

Gabriella Alves Quixabeira Oliveira, Maria Eduarda Pérez‐de‐Oliveira, Liam Robinson, Syed Ali Khurram, Keith D. Hunter, Paul M. Speight, Luiz Paulo Kowalski, Clóvis Antônio Lopes Pinto, Raísa Sales de Sá, Elismauro Francisco Mendonça, Sebastião Silvério Sousa‐Neto, Dorival de Carlucci, Fernanda Viviane Mariano, Albina Altemani, Manoela Domingues Martins, Virgílio Gonzales Zanella, Danyel Elias da Cruz Pérez, Jean Nunes dos Santos, Mário José Romañach, Aline Corrêa Abrahão, Bruno Augusto Benevenuto de Andrade, Hélder Antônio Rebelo Pontes, Jacks Jorge, Alan Roger Santos‐Silva, Márcio Ajudarte Lopes, Willie F. P. van Heerden, Pablo Agustín Vargas,

Tumors and Oncological Cases

Salivary gland tumors (SGT) are a diverse group of uncommon neoplasms that are rare in pediatric patients. This study aimed to characterize the clinicopathological profile of pediatric patients affected by SGT from a large case series derived from an international group of academic centers.A retrospective analysis of pediatric patients with SGT (0-19 years old) diagnosed between 2000 and 2021 from Brazil, South Africa, and the United Kingdom was performed. SPSS Statistics for Windows was used for a quantitative analysis of the data, with a descriptive analysis of the clinicopathological characteristics and the association between clinical variables and diagnoses.A total of 203 cases of epithelial SGT were included. Females were slightly more commonly (56.5%), with a mean age of 14.1 years. The palate was the most common site (43.5%), followed by the parotid gland (29%), lip (10%), and submandibular gland (7.5%). The predominant clinical presentation was a flesh-colored, smooth, and painless nodule. Pleomorphic adenoma (PA) was the most frequently diagnosed SGT (58.6%), followed by mucoepidermoid carcinoma (MEC) (26.6%). Surgery (90.8%) was the favored treatment option.Benign SGT in pediatric patients are more commonly benign than malignant tumors. Clinicians should keep PA and MEC in mind when assessing nodular lesions of possible salivary gland origin in pediatric patients.