The Influence of Finasteride on the Development of Prostate Cancer
2003; Massachusetts Medical Society; Volume: 349; Issue: 3 Linguagem: Inglês
10.1056/nejmoa030660
ISSN1533-4406
AutoresIan M. Thompson, Phyllis J. Goodman, Catherine M. Tangen, M. Scott Lucia, Gary J. Miller, Leslie G. Ford, Michael M. Lieber, R. Duane Cespedes, James N. Atkins, Scott M. Lippman, Susie M. Carlin, Anne Ryan, Connie M. Szczepanek, John J. Crowley, Charles A. Coltman,
Tópico(s)Hormonal and reproductive studies
ResumoAndrogens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5α-reductase, inhibits the conversion of testosterone to dihydrotestosterone, the primary androgen in the prostate, and may reduce the risk of prostate cancer.
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