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Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men

2023; Egypts Presidential Specialized Council for Education and Scientific Research; Volume: 90; Issue: 2 Linguagem: Inglês

10.21608/ejhm.2023.292762

2090-7125

Ahmed Abdel Fattah, Basheer N. Elmohamady, Salah A. El Hamshary, Hosam Abu El-Nasr,

Urinary Bladder and Prostate Research

Background: Primary premature ejaculation (PE) can be effectively treated with sildenafil citrate, according to recent research.This study evaluated sildenafil citrate efficacy in primary PE treatment, considering the female perspective.Methods: Sixty sexually active men diagnosed with primary PE were split into two groups randomly and followed for 6 months.Group A received 50 mg of sildenafil citrate one hour before sexual activity in accordance with standard dosing guidelines (not fewer than once a week), while Group B received paroxetine 20 mg daily for six months.At baseline, 3 months, and 6 months following therapy, the intravaginal ejaculatory latency time (IELT), PE grade, intercourse satisfying score (ISS), intercourse frequency, and drug-associated side effects were noted.Results: Both groups showed significant improvements in all measurements following 3 or 6 months of therapy, with no critical changes between two time points.However, sildenafil citrate was found to be significantly more effective than paroxetine in improving all parameters at both 3 and 6 months (P = 0.001).Conclusion: Sildenafil citrate is a highly beneficial treatment for primary PE and is more effective than paroxetine.